{"paper_id":"fbee971e-e6e1-40c9-a270-b69f078d7bd8","body_text":"Circulating miRNAs – a Potential Non-invasive Biomarker for Diagnosis of Endometriosis\nDOI:\nhttps://doi.org/10.7546/CRABS.2024.12.09Keywords:\nendometriosis, diagnosis, biomarker, miRNAAbstract\nEndometriosis is a debilitating disease affecting one in ten women worldwide. Due to several reasons the diagnosis is delayed for 7–11 years. Currently, the ultimate diagnostic procedure is laparoscopy followed by histological examination. The need for non-invasive biomarker is placed as a top priority according to the World Endometriosis Society.\nThe present study includes 45 females – 30 patients with endometriosis at different stages and 15 healthy controls. An expression analysis of 84 circulating miRNAs was performed comparing between different groups of participants. Ten miRNAs with the most significant expression difference between females at early stage of endometriosis, advanced stage of endometriosis and healthy controls were nominated as a potential diagnostic and prognostic biomarker using a panel of miRNAs.\nDownloads\nPublished\nHow to Cite\nIssue\nSection\nLicense\nCopyright (c) 2024 Proceedings of the Bulgarian Academy of SciencesCopyright (c) 2022 Proceedings of the Bulgarian Academy of Sciences\nCopyright is subject to the protection of the Bulgarian Copyright and Associated Rights Act. The copyright holder of all articles on this site is Proceedings of the Bulgarian Academy of Sciences. If you want to reuse any part of the content, please, contact us.","source_license":"CC0","license_restricted":false}