{"paper_id":"fa203094-ba9d-4f19-92c5-b52aea4403fb","body_text":"Abstract\nBackground\nHeavy menstrual bleeding (HMB) affects up to one-third of women, who experience HMB at some point in their lifetime, which impacts a woman's quality of life, physically, emotionally, and socially. Aiming that treatment and management options should improve the quality of life, LNG-IUS, a hormonal device, is recommended by NICE as first-line treatment for non-structural causes of HMB, such as endometrial hyperplasia, small fibroids (3cm), or adenomyosis. Patient satisfaction is crucial, as it influences treatment adherence. We conducted our study with the primary objective to evaluate continuation rate, expulsion rate, and satisfaction rate after levonorgestrel-releasing intrauterine system (LNG-IUS) insertion for HMB, aiming to promote LNG-IUS use.\nMethod\nThis retrospective cohort study included women who had LNG-IUS inserted for heavy menstrual bleeding between June 2021 and September 2022. Based on a 6% discontinuation rate for LNG-IUS, a 95% confidence level, and a 5% alpha error, the required sample size was 85. Accounting for a 15% loss to follow-up, the final sample size was 98.\nResults\nThe response was measured in all 92 women who underwent hysterectomy or expelled the device before complete follow-up. 80/92 (91.3%) were satisfied with the treatment and would recommend it to women with similar complaints. At 12-month follow-up, women had a significant increase in their mean haemoglobin values from the baseline value of 9.35 ± 2.25 gm/dL to 10.4 ± 1.4 gm/dL, and this led to improvement in symptoms of anaemia as well.\nConclusion\nLNG- IUS is highly effective in treating heavy menstrual bleeding without any major side effects; the success rate increases with good case selection. The results from the present study can be used to counsel patients with AUB.\nSimilar content being viewed by others\nReferences\nNG88 N. 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Interventions for heavy menstrual bleeding; overview of Cochrane reviews and network meta-analysis. Cochrane Database of Syst Rev. 2022;2023(2):CD013180. https://doi.org/10.1002/14651858.CD013180.pub2.\nFunding\nThis is a secondary analysis of the study which received funding from AIIMS, Nagpur.\nAuthor information\nAuthors and Affiliations\nCorresponding author\nEthics declarations\nConflict of interest\nThere is no conflict of interest among authors.\nEthics approval\nAll authors approved the manuscript and its submission to the journal. Ethical committee has approved this study.\nConsent for publication\nThis manuscript has not been published and is not under consideration for publication in any other journal.\nInformed consent\nInformed consent was obtained from all individual participants included in the study. The participants have consented to the submission and publication of relevant data. Identifiable information has been omitted or anonymized to preserve confidentiality.\nAdditional information\nPublisher's Note\nSpringer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.\nAvantika Gupta, MD, OBGY, Associate Professor; Neha Gangane, MD OBGY, Associate Professor; Bishnupriya Moharana, MBBS, Junior Resident; Minal Pradip Dhanvij, MS OBGY, Senior Resident; Medha Davile, MD OBGY, Associate Professor; Shuchita Mundle, MD OBGY, Professor and HOD.\nRights and permissions\nAbout this article\nCite this article\nGupta, A., Gangane, N., Moharana, B. et al. Self-Reported Patient’s Continuation Rate, Complications, and Content (3c’s Study) with Levonorgestrel Intrauterine System (LNG-IUS) for Heavy Menstrual Bleeding. J Obstet Gynecol India 76, 272–275 (2026). https://doi.org/10.1007/s13224-025-02152-2\nReceived:\nAccepted:\nPublished:\nVersion of record:\nIssue date:\nDOI: https://doi.org/10.1007/s13224-025-02152-2","source_license":"public-domain-us","license_restricted":false}