{"paper_id":"edb6bd5c-5823-412c-8f7b-e96894a95b42","body_text":"Abstract\nEndometriosis, defined as the presence of endometrial tissue outside the uterus, is an estrogen-dependent disease which causes pelvic pain and subfertility in women of reproductive age. The condition has a dramatic impact on the professional, social and marital life of sufferers. Direct and indirect evidence suggests that angiogenesis is required for the development and persistence of endometriosis. In this review the state-of-the-art with regard to our understanding of the role of angiogenesis in the ectopic implantation and survival of menstrual endometrial tissue will be discussed.\nSimilar content being viewed by others\nReferences\nNisolle M, Donnez J. (1997). Peritoneal endometriosis, ovarian endometriosis, and adenomyotic nodules of the rectovaginal septum are three different entities. Fertil Steril 68(4):585–96\nSampson JA. (1927). 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Groothuis, Research Institute GROW, Department of Obstetrics and Gynecology, Academisch Ziekenhuis Maastricht, Peter Debyelaan 25, 6229 HX Maastricht, The Netherlands. Tel:␣+31-43-3876625; Fax: +31-43-3876613; E-mail: patrick.groothuis@ path.unimaas.nl\nRights and permissions\nAbout this article\nCite this article\nGroothuis, P., Nap, A., Winterhager, E. et al. Vascular development in endometriosis. Angiogenesis 8, 147–156 (2005). https://doi.org/10.1007/s10456-005-9005-x\nReceived:\nAccepted:\nPublished:\nIssue date:\nDOI: https://doi.org/10.1007/s10456-005-9005-x","source_license":"CC0","license_restricted":false}