{"paper_id":"e7e7a6e2-9075-42b5-8d51-594f37ebfe7c","body_text":"81\nItal J Gynaecol Obstet 2023, 35, Supplement N.1 Abstract\nPrevious surgery for endometriosis: a further risk for obstetric \ncomplications? \nSilvia Vannuccini, Francesco La Torre *, Ernesto Gallucci, Federico Toscano, Agostino Ruotolo, \nTommaso Capezzuoli, Federico Mecacci, Felice Petraglia\nCareggi University Hospital, University of Florence, Florence, Italy.\nDOI: 10.36129/jog.2022.S80\nObjective. A number of evidence has shown that endome-\ntriosis is associated with an increased incidence of obstetric \ncomplications, but it is still unknown if other variables relat-\ned to the disease influence the outcome. Thus, the aim of the \nstudy was to evaluate whether a history of surgery represents \nan additional risk factor for adverse pregnancy and delivery \noutcome among women with endometriosis.\nMaterials and Methods. A retrospective observational cohort \nstudy on prospectively collected data was conducted in a sin-\ngle tertiary referral center for both endometriosis and high-risk \npregnancy between 2019 and 2021. Women with a history of \nendometriosis, diagnosed either by imaging or by histological \nconfirmation after surgery, who were followed up and deliv-\nered after singleton pregnancy were included. Women with and \nwithout previous surgical treatment for endometriosis were \ncompared in terms of maternal characteristics, mode of concep-\ntion, pregnancy management, obstetric complications, delivery \nand postpartum outcome, pregnancy and delivery outcome. \nResults. The study population included 162 cases and 103 \n(63%) had 1 or more surgery for endometriosis. A high inci-\ndence of preterm births, placental disorders, gestational dia-\nbetes, caesarean section (CS) and postpartum haemorrhage \n(PPH) was found compared to non-endometriosis patients. \nHowever, women with a history of surgery for endometrio-\nsis had further increase of CS (47%) and PPH rate (27%) com-\npared to those conservatively managed. No difference was \nfound in terms of other obstetric complications. \nConclusions. Pregnant women with a history of surgery for \nendometriosis should be considered at high risk for peripar -\ntum and postpartum adverse outcomes.","source_license":"CC0","license_restricted":false}