{"paper_id":"e6019c02-939b-4ee2-a1b7-853e879ea796","body_text":"Report error Found 33 Enz. Inhib. hit(s) with all data for entry = 50008151\nTarget17-beta-hydroxysteroid dehydrogenase type 1(Human)\nHelmholtz Institute For Pharmaceutical Research Saarland (Hips)\nCurated by ChEMBL\nHelmholtz Institute For Pharmaceutical Research Saarland (Hips)\nCurated by ChEMBL\nAffinity DataIC50: 0.400nMAssay Description:Inhibition of human placental cytosolic fraction 17beta-HSD1 using [3H]-E1 as substrate in presence of NAD+ by radio-HPLC analysisMore data for this Ligand-Target Pair\nTarget17-beta-hydroxysteroid dehydrogenase type 1(Human)\nHelmholtz Institute For Pharmaceutical Research Saarland (Hips)\nCurated by ChEMBL\nHelmholtz Institute For Pharmaceutical Research Saarland (Hips)\nCurated by ChEMBL\nAffinity DataIC50: 0.5nMAssay Description:Inhibition of human placental cytosolic fraction 17beta-HSD1 using [3H]-E1 as substrate in presence of NAD+ by radio-HPLC analysisMore data for this Ligand-Target Pair\nTarget17-beta-hydroxysteroid dehydrogenase type 1(Human)\nHelmholtz Institute For Pharmaceutical Research Saarland (Hips)\nCurated by ChEMBL\nHelmholtz Institute For Pharmaceutical Research Saarland (Hips)\nCurated by ChEMBL\nAffinity DataIC50: 0.5nMAssay Description:Inhibition of human placental cytosolic fraction 17beta-HSD1 using [3H]-E1 as substrate in presence of NAD+ by radio-HPLC analysisMore data for this Ligand-Target Pair\nTarget17-beta-hydroxysteroid dehydrogenase type 1(Human)\nHelmholtz Institute For Pharmaceutical Research Saarland (Hips)\nCurated by ChEMBL\nHelmholtz Institute For Pharmaceutical Research Saarland (Hips)\nCurated by ChEMBL\nAffinity DataIC50: 0.900nMAssay Description:Inhibition of human placental cytosolic fraction 17beta-HSD1 using [3H]-E1 as substrate in presence of NAD+ by radio-HPLC analysisMore data for this Ligand-Target Pair\nTarget17-beta-hydroxysteroid dehydrogenase type 2(Human)\nHelmholtz Institute For Pharmaceutical Research Saarland (Hips)\nCurated by ChEMBL\nHelmholtz Institute For Pharmaceutical Research Saarland (Hips)\nCurated by ChEMBL\nAffinity DataIC50: 1.10nMAssay Description:Inhibition of human placental microsomal fraction 17beta-HSD2 using [3H]-E2 as substrate in presence of NAD+ by radio-HPLC analysisMore data for this Ligand-Target Pair\nTarget17-beta-hydroxysteroid dehydrogenase type 2(Human)\nHelmholtz Institute For Pharmaceutical Research Saarland (Hips)\nCurated by ChEMBL\nHelmholtz Institute For Pharmaceutical Research Saarland (Hips)\nCurated by ChEMBL\nAffinity DataIC50: 1.30nMAssay Description:Inhibition of human placental microsomal fraction 17beta-HSD2 using [3H]-E2 as substrate in presence of NAD+ by radio-HPLC analysisMore data for this Ligand-Target Pair\nTarget17-beta-hydroxysteroid dehydrogenase type 1(Human)\nHelmholtz Institute For Pharmaceutical Research Saarland (Hips)\nCurated by ChEMBL\nHelmholtz Institute For Pharmaceutical Research Saarland (Hips)\nCurated by ChEMBL\nAffinity DataIC50: 1.5nMAssay Description:Inhibition of human placental cytosolic fraction 17beta-HSD1 using [3H]-E1 as substrate in presence of NAD+ by radio-HPLC analysisMore data for this Ligand-Target Pair\nTarget17-beta-hydroxysteroid dehydrogenase type 2(Human)\nHelmholtz Institute For Pharmaceutical Research Saarland (Hips)\nCurated by ChEMBL\nHelmholtz Institute For Pharmaceutical Research Saarland (Hips)\nCurated by ChEMBL\nAffinity DataIC50: 2nMAssay Description:Inhibition of human placental microsomal fraction 17beta-HSD2 using [3H]-E2 as substrate in presence of NAD+ by radio-HPLC analysisMore data for this Ligand-Target Pair\nTarget17-beta-hydroxysteroid dehydrogenase type 1(Human)\nHelmholtz Institute For Pharmaceutical Research Saarland (Hips)\nCurated by ChEMBL\nHelmholtz Institute For Pharmaceutical Research Saarland (Hips)\nCurated by ChEMBL\nAffinity DataIC50: 3nMAssay Description:Inhibition of human placental cytosolic fraction 17beta-HSD1 using [3H]-E1 as substrate in presence of NAD+ by radio-HPLC analysisMore data for this Ligand-Target Pair\nTarget17-beta-hydroxysteroid dehydrogenase type 1(Human)\nHelmholtz Institute For Pharmaceutical Research Saarland (Hips)\nCurated by ChEMBL\nHelmholtz Institute For Pharmaceutical Research Saarland (Hips)\nCurated by ChEMBL\nAffinity DataIC50: 6nMAssay Description:Inhibition of human placental cytosolic fraction 17beta-HSD1 using [3H]-E1 as substrate in presence of NAD+ by radio-HPLC analysisMore data for this Ligand-Target Pair\nTarget17-beta-hydroxysteroid dehydrogenase type 2(Human)\nHelmholtz Institute For Pharmaceutical Research Saarland (Hips)\nCurated by ChEMBL\nHelmholtz Institute For Pharmaceutical Research Saarland (Hips)\nCurated by ChEMBL\nAffinity DataIC50: 6nMAssay Description:Inhibition of human placental microsomal fraction 17beta-HSD2 using [3H]-E2 as substrate in presence of NAD+ by radio-HPLC analysisMore data for this Ligand-Target Pair\nTarget17-beta-hydroxysteroid dehydrogenase type 1(Human)\nHelmholtz Institute For Pharmaceutical Research Saarland (Hips)\nCurated by ChEMBL\nHelmholtz Institute For Pharmaceutical Research Saarland (Hips)\nCurated by ChEMBL\nAffinity DataIC50: 6nMAssay Description:Inhibition of human placental cytosolic fraction 17beta-HSD1 using [3H]-E1 as substrate in presence of NAD+ by radio-HPLC analysisMore data for this Ligand-Target Pair\nTarget17-beta-hydroxysteroid dehydrogenase type 2(Human)\nHelmholtz Institute For Pharmaceutical Research Saarland (Hips)\nCurated by ChEMBL\nHelmholtz Institute For Pharmaceutical Research Saarland (Hips)\nCurated by ChEMBL\nAffinity DataIC50: 7.30nMAssay Description:Inhibition of human placental microsomal fraction 17beta-HSD2 using [3H]-E2 as substrate in presence of NAD+ by radio-HPLC analysisMore data for this Ligand-Target Pair\nTarget17-beta-hydroxysteroid dehydrogenase type 1(Human)\nHelmholtz Institute For Pharmaceutical Research Saarland (Hips)\nCurated by ChEMBL\nHelmholtz Institute For Pharmaceutical Research Saarland (Hips)\nCurated by ChEMBL\nAffinity DataIC50: 8nMAssay Description:Inhibition of human placental cytosolic fraction 17beta-HSD1 using [3H]-E1 as substrate in presence of NAD+ by radio-HPLC analysisMore data for this Ligand-Target Pair\nTarget17-beta-hydroxysteroid dehydrogenase type 2(Human)\nHelmholtz Institute For Pharmaceutical Research Saarland (Hips)\nCurated by ChEMBL\nHelmholtz Institute For Pharmaceutical Research Saarland (Hips)\nCurated by ChEMBL\nAffinity DataIC50: 9.5nMAssay Description:Inhibition of human placental microsomal fraction 17beta-HSD2 using [3H]-E2 as substrate in presence of NAD+ by radio-HPLC analysisMore data for this Ligand-Target Pair\nTarget17-beta-hydroxysteroid dehydrogenase type 2(Human)\nHelmholtz Institute For Pharmaceutical Research Saarland (Hips)\nCurated by ChEMBL\nHelmholtz Institute For Pharmaceutical Research Saarland (Hips)\nCurated by ChEMBL\nAffinity DataIC50: 15nMAssay Description:Inhibition of human placental microsomal fraction 17beta-HSD2 using [3H]-E2 as substrate in presence of NAD+ by radio-HPLC analysisMore data for this Ligand-Target Pair\nTarget17-beta-hydroxysteroid dehydrogenase type 1(Human)\nHelmholtz Institute For Pharmaceutical Research Saarland (Hips)\nCurated by ChEMBL\nHelmholtz Institute For Pharmaceutical Research Saarland (Hips)\nCurated by ChEMBL\nAffinity DataIC50: 15nMAssay Description:Inhibition of human placental cytosolic fraction 17beta-HSD1 using [3H]-E1 as substrate in presence of NAD+ by radio-HPLC analysisMore data for this Ligand-Target Pair\nTarget17-beta-hydroxysteroid dehydrogenase type 2(Human)\nHelmholtz Institute For Pharmaceutical Research Saarland (Hips)\nCurated by ChEMBL\nHelmholtz Institute For Pharmaceutical Research Saarland (Hips)\nCurated by ChEMBL\nAffinity DataIC50: 18nMAssay Description:Inhibition of human placental microsomal fraction 17beta-HSD2 using [3H]-E2 as substrate in presence of NAD+ by radio-HPLC analysisMore data for this Ligand-Target Pair\nTarget17-beta-hydroxysteroid dehydrogenase type 2(Human)\nHelmholtz Institute For Pharmaceutical Research Saarland (Hips)\nCurated by ChEMBL\nHelmholtz Institute For Pharmaceutical Research Saarland (Hips)\nCurated by ChEMBL\nAffinity DataIC50: 18nMAssay Description:Inhibition of human placental microsomal fraction 17beta-HSD2 using [3H]-E2 as substrate in presence of NAD+ by radio-HPLC analysisMore data for this Ligand-Target Pair\nTarget17-beta-hydroxysteroid dehydrogenase type 2(Human)\nHelmholtz Institute For Pharmaceutical Research Saarland (Hips)\nCurated by ChEMBL\nHelmholtz Institute For Pharmaceutical Research Saarland (Hips)\nCurated by ChEMBL\nAffinity DataIC50: 18nMAssay Description:Inhibition of human placental microsomal fraction 17beta-HSD2 using [3H]-E2 as substrate in presence of NAD+ by radio-HPLC analysisMore data for this Ligand-Target Pair\nTargetEstradiol 17-beta-dehydrogenase 2(Mouse)\nHelmholtz Institute For Pharmaceutical Research Saarland (Hips)\nCurated by ChEMBL\nHelmholtz Institute For Pharmaceutical Research Saarland (Hips)\nCurated by ChEMBL\nAffinity DataIC50: 25nMAssay Description:Inhibition of mouse liver homogenate 17beta-HSD2 using [3H]-E2 as substrate in presence of NAD+ by radio-HPLC analysisMore data for this Ligand-Target Pair\nTargetEstradiol 17-beta-dehydrogenase 2(Mouse)\nHelmholtz Institute For Pharmaceutical Research Saarland (Hips)\nCurated by ChEMBL\nHelmholtz Institute For Pharmaceutical Research Saarland (Hips)\nCurated by ChEMBL\nAffinity DataIC50: 34nMAssay Description:Inhibition of mouse liver homogenate 17beta-HSD2 using [3H]-E2 as substrate in presence of NAD+ by radio-HPLC analysisMore data for this Ligand-Target Pair\nTarget17-beta-hydroxysteroid dehydrogenase type 1(Human)\nHelmholtz Institute For Pharmaceutical Research Saarland (Hips)\nCurated by ChEMBL\nHelmholtz Institute For Pharmaceutical Research Saarland (Hips)\nCurated by ChEMBL\nAffinity DataIC50: 35nMAssay Description:Inhibition of human placental cytosolic fraction 17beta-HSD1 using [3H]-E1 as substrate in presence of NAD+ by radio-HPLC analysisMore data for this Ligand-Target Pair\nTarget17-beta-hydroxysteroid dehydrogenase type 2(Human)\nHelmholtz Institute For Pharmaceutical Research Saarland (Hips)\nCurated by ChEMBL\nHelmholtz Institute For Pharmaceutical Research Saarland (Hips)\nCurated by ChEMBL\nAffinity DataIC50: 41nMAssay Description:Inhibition of human placental microsomal fraction 17beta-HSD2 using [3H]-E2 as substrate in presence of NAD+ by radio-HPLC analysisMore data for this Ligand-Target Pair\nTarget17-beta-hydroxysteroid dehydrogenase type 1(Human)\nHelmholtz Institute For Pharmaceutical Research Saarland (Hips)\nCurated by ChEMBL\nHelmholtz Institute For Pharmaceutical Research Saarland (Hips)\nCurated by ChEMBL\nAffinity DataIC50: 44nMAssay Description:Inhibition of human placental cytosolic fraction 17beta-HSD1 using [3H]-E1 as substrate in presence of NAD+ by radio-HPLC analysisMore data for this Ligand-Target Pair\nTarget17-beta-hydroxysteroid dehydrogenase type 1(Human)\nHelmholtz Institute For Pharmaceutical Research Saarland (Hips)\nCurated by ChEMBL\nHelmholtz Institute For Pharmaceutical Research Saarland (Hips)\nCurated by ChEMBL\nAffinity DataIC50: 59nMAssay Description:Inhibition of human placental cytosolic fraction 17beta-HSD1 using [3H]-E1 as substrate in presence of NAD+ by radio-HPLC analysisMore data for this Ligand-Target Pair\nTarget17-beta-hydroxysteroid dehydrogenase type 2(Human)\nHelmholtz Institute For Pharmaceutical Research Saarland (Hips)\nCurated by ChEMBL\nHelmholtz Institute For Pharmaceutical Research Saarland (Hips)\nCurated by ChEMBL\nAffinity DataIC50: 75nMAssay Description:Inhibition of human placental microsomal fraction 17beta-HSD2 using [3H]-E2 as substrate in presence of NAD+ by radio-HPLC analysisMore data for this Ligand-Target Pair\nTarget17-beta-hydroxysteroid dehydrogenase type 2(Human)\nHelmholtz Institute For Pharmaceutical Research Saarland (Hips)\nCurated by ChEMBL\nHelmholtz Institute For Pharmaceutical Research Saarland (Hips)\nCurated by ChEMBL\nAffinity DataIC50: 76nMAssay Description:Inhibition of human placental microsomal fraction 17beta-HSD2 using [3H]-E2 as substrate in presence of NAD+ by radio-HPLC analysisMore data for this Ligand-Target Pair\nTarget17-beta-hydroxysteroid dehydrogenase type 1(Human)\nHelmholtz Institute For Pharmaceutical Research Saarland (Hips)\nCurated by ChEMBL\nHelmholtz Institute For Pharmaceutical Research Saarland (Hips)\nCurated by ChEMBL\nAffinity DataIC50: 80nMAssay Description:Inhibition of human placental cytosolic fraction 17beta-HSD1 using [3H]-E1 as substrate in presence of NAD+ by radio-HPLC analysisMore data for this Ligand-Target Pair\nTargetEstradiol 17-beta-dehydrogenase 2(Mouse)\nHelmholtz Institute For Pharmaceutical Research Saarland (Hips)\nCurated by ChEMBL\nHelmholtz Institute For Pharmaceutical Research Saarland (Hips)\nCurated by ChEMBL\nAffinity DataIC50: 80nMAssay Description:Inhibition of mouse liver homogenate 17beta-HSD2 using [3H]-E2 as substrate in presence of NAD+ by radio-HPLC analysisMore data for this Ligand-Target Pair\nTarget17-beta-hydroxysteroid dehydrogenase type 2(Human)\nHelmholtz Institute For Pharmaceutical Research Saarland (Hips)\nCurated by ChEMBL\nHelmholtz Institute For Pharmaceutical Research Saarland (Hips)\nCurated by ChEMBL\nAffinity DataIC50: 159nMAssay Description:Inhibition of human placental microsomal fraction 17beta-HSD2 using [3H]-E2 as substrate in presence of NAD+ by radio-HPLC analysisMore data for this Ligand-Target Pair\nTarget17-beta-hydroxysteroid dehydrogenase type 2(Human)\nHelmholtz Institute For Pharmaceutical Research Saarland (Hips)\nCurated by ChEMBL\nHelmholtz Institute For Pharmaceutical Research Saarland (Hips)\nCurated by ChEMBL\nAffinity DataIC50: 239nMAssay Description:Inhibition of human placental microsomal fraction 17beta-HSD2 using [3H]-E2 as substrate in presence of NAD+ by radio-HPLC analysisMore data for this Ligand-Target Pair\nTarget17-beta-hydroxysteroid dehydrogenase type 1(Human)\nHelmholtz Institute For Pharmaceutical Research Saarland (Hips)\nCurated by ChEMBL\nHelmholtz Institute For Pharmaceutical Research Saarland (Hips)\nCurated by ChEMBL\nAffinity DataIC50: 899nMAssay Description:Inhibition of human placental cytosolic fraction 17beta-HSD1 using [3H]-E1 as substrate in presence of NAD+ by radio-HPLC analysisMore data for this Ligand-Target Pair","source_license":"public-domain-us","license_restricted":false}