{"paper_id":"e4429ca7-e955-4c68-9e86-d28f27d334c4","body_text":"Skinfold thickness in Ukrainian young women with genital endometriosis without and with regard to somatotype\nDOI:\nhttps://doi.org/10.31393/reports-vnmedical-2025-29(2)-07Keywords:\nobstetrics and gynecology, practically healthy and young women with genital endometriosis, anthropometry, skinfold thickness, somatotype.Abstract\nAnnotation. Genital endometriosis is one of the most common gynecological diseases of reproductive age, the pathogenesis of which remains multifactorial and insufficiently understood. Features of the body fat component may play a role in the course and severity of symptoms of this disease. Studying the thickness of skin-fat folds allows us to assess individual anthropometric characteristics, which may have diagnostic and prognostic significance. Taking into account the somatotype of patients opens up new opportunities for understanding the relationships between the morphofunctional features of the body and the development of pathology. The aim of the study is to determine the characteristics of skinfold thickness in Ukrainian young women with genital endometriosis without and taking into account the somatotype. Skinfold thickness was determined in 89 Ukrainian young women with genital endometriosis. The primary skinfold thickness indicators of 78 practically healthy Ukrainian young women served as controls. Statistical processing of the obtained results was carried out in the licensed package «Statistica 6.0» using non-parametric evaluation methods. It was found that in patients with genital endometriosis of Ukrainian young women, regardless of somatotype, and representatives of mesomorphic and ectomorphic somatotypes, the skinfold thickness on the upper limb and at the lower angle of the scapula have significantly lower values (most pronounced in ectomorphs), and the skinfold thickness on the lower leg in patients with mesomorphic and ecto-mesomorphic somatotypes and the folds on the chest in girls regardless of somatotype, mesomorphs and ecto-mesomorphs, on the contrary, are significantly higher or tend to be higher than the corresponding folds in practically healthy Ukrainian young women of similar groups. When comparing skinfold thickness between sick Ukrainian young women of different somatotypes, in almost all cases, significantly higher or a tendency to higher values were found in young women of mesomorphic somatotype compared to young women of ectomorphic somatotype.\nDownloads\nReferences\nBecker, C. M., Bokor, A., Heikinheimo, O., Horne, A., Jansen, F., Kiesel, L., ... & Vermeulen, N. (2022). ESHRE guideline: endometriosis. Human reproduction open, 2022(2), hoac009. doi: 10.1093/hropen/hoac009\nCarter, J. L., & Heath, B. H. (1990). Somatotyping – development and applications. Cambridge University Press.\nComstock, I. A., Diaz-Gimeno, P., Cabanillas, S., Bellver, J., Sebastian-Leon, P., Shah, M., ... & Lathi, R. B. (2017). Does an increased body mass index affect endometrial gene expression patterns in infertile patients? A functional genomics analysis. Fertility and sterility, 107(3), 740-748. doi: 10.1016/j.fertnstert.2016.11.009\nDi Bello, J. R., He, J., Weaver, J., Liu, S., & Arbelaez Casas, F. (2020). Epidemiology of endometriosis in UK adolescents. Eur Gynecol Obstet, 2(4), 218-22.\nFacchin, F., Barbara, G., Saita, E., Mosconi, P., Roberto, A., Fedele, L., & Vercellini, P. (2015). Impact of endometriosis on quality of life and mental health: pelvic pain makes the difference. Journal of Psychosomatic Obstetrics & Gynecology, 36(4), 135-141. doi: 10.3109/0167482X.2015.1074173\nFerreira, A. L. L., Bessa, M. M. M., Drezett, J., & de Abreu, L. C. (2016). Quality of life of the woman carrier of endometriosis: systematized review. Reprodução & Climatério, 31(1), 48-54. doi: 10.1016/j.recli.2015.12.002\nJu, H., Jones, M., & Mishra, G. D. (2015). A U-shaped relationship between body mass index and dysmenorrhea: a longitudinal study. PloS one, 10(7), e0134187. doi: 10.1371/journal.pone.0134187\nKajiyama, H., Suzuki, S., Yoshihara, M., Tamauchi, S., Yoshikawa, N., Niimi, K., ... & Kikkawa, F. (2019). Endometriosis and cancer. Free Radical Biology and Medicine, (133), 186-192. doi: 10.1016/j.freeradbiomed.2018.12.015\nKhan, Z., Zanfagnin, V., El-Nashar, S. A., Famuyide, A. O., Daftary, G. S., & Hopkins, M. R. (2017). Risk factors, clinical presentation, and outcomes for abdominal wall endometriosis. Journal of minimally invasive gynecology, 24(3), 478-484. doi: 10.1016/j.jmig.2017.01.005\nKnific, T., Osredkar, J., Smrkolj, Š., Tonin, I., Vouk, K., Blejec, A., ... & Rižner, T. L. (2017). Novel algorithm including CA-125, HE4 and body mass index in the diagnosis of endometrial cancer. Gynecologic Oncology, 147(1), 126-132. doi: 10.1016/j.ygyno.2017.07.130\nKucherenko, O., Chaika, H., Kostyuk, A., Storozhuk, M., & Kostyuk, I. (2020). Age-related aspects of the development of abnormal uterine bleeding in girls of different somatotypes. Georgian medical news, (308), 25-31. PMID: 33395636\nLaganà, A. S., Garzon, S., Götte, M., Viganò, P., Franchi, M., Ghezzi, F., & Martin, D. C. (2019). The pathogenesis of endometriosis: molecular and cell biology insights. International journal of molecular sciences, 20(22), 5615. doi: 10.3390/ijms20225615\nMarinho, M. C., Magalhaes, T. F., Fernandes, L. F. C., Augusto, K. L., Brilhante, A. V., & Bezerra, L. R. (2018). Quality of life in women with endometriosis: an integrative review. Journal of Women's Health, 27(3), 399-408. doi: 10.1089/jwh.2017.6397\nMolina Rodríguez, R. (2024). Epidemiology, clinic and evolution in patients with endometriosis. Revista de Obstetricia y Ginecología de Venezuela, 84(3), 299-306. doi: 10.51288/00840311\nMorassutto, C., Monasta, L., Ricci, G., Barbone, F., & Ronfani, L. (2016). Incidence and estimated prevalence of endometriosis and adenomyosis in Northeast Italy: a data linkage study. PloS one, 11(4), e0154227. doi: 10.1371/journal.pone.0154227\nQin, H., Lin, Z., Vásquez, E., Luan, X., Guo, F., & Xu, L. (2021). Association between obesity and the risk of uterine fibroids: a systematic review and meta-analysis. J Epidemiol Community Health, 75(2), 197-204. doi: 10.1136/jech-2019-213364\nRadivojevic, U. D., Lazovic, G. B., Kravic-Stevovic, T. K., Puzigaca, Z. D., Canovic, F. M., Nikolic, R. R., & Milicevic, S. M. (2014). Differences in anthropometric and ultrasonographic parameters between adolescent girls with regular and irregular menstrual cycles: a case-study of 835 cases. Journal of pediatric and adolescent gynecology, 27(4), 227-231. doi: 10.1016/j.jpag.2013.11.007\nSarafinjuk, L. A., Khapitska, O. P., Smolko, N. M., Smolko, D. G., Fedoniuk, L. Y., Sarafinjuk, P. V., & Matceyko, I. I. (2020). Ontogenetic features of sonographic indicators of the uterus in acrobats of the Ukrainian ethnic group. Wiadomosci lekarskie (Warsaw, Poland: 1960), 73(6), 1194-1198. PMID: 32723952\nSecord, A. A., Hasselblad, V., Von Gruenigen, V. E., Gehrig, P. A., Modesitt, S. C., Bae-Jump, V., & Havrilesky, L. J. (2016). Body mass index and mortality in endometrial cancer: A systematic review and meta-analysis. Gynecologic oncology, 140(1), 184-190. doi: 10.1016/j.ygyno.2015.10.020\nShaparenko, P. P. (2000). Антропометрія [Anthropometry]. Вінниця: ВДМУ ім. М. І. Пирогова – Vinnytsia: VDMU im. М. І. Pyrogova.\nTak, Y. J., Lee, S. Y., Park, S. K., Kim, Y. J., Lee, J. G., Jeong, D. W., ... & Yi, Y. H. (2016). Association between uterine leiomyoma and metabolic syndrome in parous premenopausal women: A case–control study. Medicine, 95(46), e5325. doi: 10.1097/MD.0000000000005325\nUpson, K. (2020). Environmental risk factors for endometriosis: A critical evaluation of studies and recommendations from the epidemiologic perspective. Current epidemiology reports, (7), 149-170. doi: 10.1007/s40471-020-00236-3\nWang, Y., Nicholes, K., & Shih, I. M. (2020). The origin and pathogenesis of endometriosis. Annual Review of Pathology: Mechanisms of Disease, 15(1), 71-95. doi: 10.1146/annurev-pathmechdis-012419-032654\nZhang, S., Gong, T. T., Wang, H. Y., Zhao, Y. H., & Wu, Q. J. (2021). Global, regional, and national endometriosis trends from 1990 to 2017. Annals of the New York Academy of Sciences, 1484(1), 90-101. doi: 10.1111/nyas.14468","source_license":"CC0","license_restricted":false}