{"paper_id":"e21a16d4-fb22-44d3-8191-c268ae89dfb2","body_text":"Previously submitted to: JMIR Formative Research (no longer under consideration since May 19, 2026)\nDate Submitted: Jun 14, 2025\nOpen Peer Review Period: Jun 14, 2025 - Aug 9, 2025\n(closed for review but you can still tweet)\nNOTE: This is an unreviewed Preprint\nWarning: This is a unreviewed preprint (What is a preprint?). Readers are warned that the document has not been peer-reviewed by expert/patient reviewers or an academic editor, may contain misleading claims, and is likely to undergo changes before final publication, if accepted, or may have been rejected/withdrawn (a note \"no longer under consideration\" will appear above).\nPeer review me: Readers with interest and expertise are encouraged to sign up as peer-reviewer, if the paper is within an open peer-review period (in this case, a \"Peer Review Me\" button to sign up as reviewer is displayed above). All preprints currently open for review are listed here. Outside of the formal open peer-review period we encourage you to tweet about the preprint.\nCitation: Please cite this preprint only for review purposes or for grant applications and CVs (if you are the author).\nFinal version: If our system detects a final peer-reviewed \"version of record\" (VoR) published in any journal, a link to that VoR will appear below. Readers are then encourage to cite the VoR instead of this preprint.\nSettings: If you are the author, you can login and change the preprint display settings, but the preprint URL/DOI is supposed to be stable and citable, so it should not be removed once posted.\nSubmit: To post your own preprint, simply submit to any JMIR journal, and choose the appropriate settings to expose your submitted version as preprint.\nWarning: This is an author submission that is not peer-reviewed or edited. Preprints - unless they show as \"accepted\" - should not be relied on to guide clinical practice or health-related behavior and should not be reported in news media as established information.\nEvaluation of Factors Associated with Endometriosis and Clinical Treatments in Bangladesh: Case-control study\nABSTRACT\nBackground:\nEndometriosis is a gynecological condition that involves the implantation of endometrial tissue outside the uterine cavity. About 1.2 million women are suffering from this disease in Bangladesh\nObjective:\nThe purpose of this study was to explore the factors associated with endometriosis, symptoms, and clinical treatment in Bangladesh.\nMethods:\nIn this case-control study, out of 162 women, 82 had endometriosis confirmed with laparoscopy/ transvaginal ultrasound and 80 were included in the control group with normal pelvic ultrasound. All were asked to fill out a questionnaire containing demographics, reproductive, and menstrual status. Comparisons between the two groups were done using an Independent t-test, Chi-square test and logistic regression model. P-value < .05 was considered statistically significant.\nResults:\nThe prevalence of endometriosis was higher with, age 25.78 ± 5.36 (P = .01), marital status, and BMI (P < .05). The most common symptoms were dysmenorrhea, excessive bleeding, cramping etc. Infertility (OR:2.21; %95CI: 1.07–4.53; P = .03), thyroid imbalance (OR:3.44; %95CI: 1.47–8.03; P = .004), irregular menstruation (OR:5.76; %95CI: 2.12–15.60; P = .001), age at menarche (OR:2.54; %95CI: 1.04–6.21; P = .04) were the factor that associated with endometriosis. Endometriosis was diagnosed most frequently by TVS (transvaginal ultrasound) at 45.1%, NSAI (nonsteroidal aromatase inhibitors) at 22.8% was the most commonly utilized medicine, and 17.9% of patients undergo laparoscopy for surgical treatment\nConclusions:\nThis study identified several factors significantly associated with endometriosis among infertile women in Bangladesh. The prevalence of endometriosis was notably higher among women with increased age, specific marital statuses, and elevated BMI. Common symptoms included dysmenorrhea, excessive bleeding, and cramping. Key associated factors were infertility, thyroid imbalance, irregular menstruation and early age at menarche. Transvaginal ultrasound emerged as the most frequently used diagnostic method, while nonsteroidal aromatase inhibitors were the most common form of medical treatment. These findings emphasize the importance of early screening and targeted interventions, as well as the need to enhance clinical awareness and access to care for women at risk of endometriosis.\nCitation\nRequest queued. Please wait while the file is being generated. It may take some time.\nCopyright\n© The authors. All rights reserved. This is a privileged document currently under peer-review/community review (or an accepted/rejected manuscript). Authors have provided JMIR Publications with an exclusive license to publish this preprint on it's website for review and ahead-of-print citation purposes only. While the final peer-reviewed paper may be licensed under a cc-by license on publication, at this stage authors and publisher expressively prohibit redistribution of this draft paper other than for review purposes.","source_license":"CC0","license_restricted":false}