{"paper_id":"e03aa4de-f678-4165-a42b-a88883ea7b52","body_text":"Abstract\nPurpose\nTo investigate the relationship between pain intensity and insomnia frequency in women with a diagnosis of deep endometriosis. The hypothesis is that these patients with moderate or severe pain have a higher frequency of insomnia than those with mild or no pain.\nMethods\nWe conducted a cross-sectional study of women with deep endometriosis categorized by pelvic pain intensity based on a numerical scale. Insomnia was assessed through a self-reported questionnaire, and multiple logistic regression was used to control for confounders between pain and insomnia.\nResults\nWe included 234 women in the study, 39 (17%) without pelvic pain; 66 (29%) with mild pain; 53 (23%) moderate pain; and 76 (32%) severe pain. Twenty-nine (74%) pain-free women and 50 (75%) with mild pain had no insomnia; only 3 (8%) of the former and 3 (4%) of the latter group had severe insomnia. However, twenty-nine (55%) women with moderate pain and 37 (48%) with severe pain had insomnia. The logistic regression model showed that moderate to severe pain increased insomnia 2.8 times, twice for every 10 years of pain duration, and twice in women with low education levels.\nConclusions\nWomen with moderate or severe pain had a high frequency of insomnia, increasing management complexity in patients with deep endometriosis. Pain intensity, pain duration, and low education level increased the chance of insomnia in those patients.\nSimilar content being viewed by others\nData availability\nThe datasets generated during and/or analyzed during the current study are not publicly available due to the sigil’s patient information. 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R.: results interpretation; discussion; and review.\nCorresponding author\nEthics declarations\nEthical approval\nAll procedures performed in studies involving human participants were in accordance with the ethical standards of the institutional and/or national research committee (The University of the State of Rio de Janeiro—CAAE: 18261019.4.0000.5259) and with the 1964 Helsinki declaration and its later amendments or comparable ethical standards.\nInformed consent\nInformed consent was obtained from all individual participants included in the study.\nConflict of interest\nThe authors declare no competing interests.\nAdditional information\nPublisher's note\nSpringer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.\nSynopsis\nWomen with deep endometriosis experiencing moderate or severe pain have a high frequency of insomnia. Low education level and pain duration also play a role in this relationship.\nRights and permissions\nAbout this article\nCite this article\nde Souza, R.J., Vilella, N.R. & Oliveira, M.A.P. The relationship between pain intensity and insomnia in women with deep endometriosis, a cross-sectional study. Sleep Breath 27, 441–447 (2023). https://doi.org/10.1007/s11325-022-02622-1\nReceived:\nRevised:\nAccepted:\nPublished:\nVersion of record:\nIssue date:\nDOI: https://doi.org/10.1007/s11325-022-02622-1","source_license":"CC0","license_restricted":false}