{"paper_id":"d9c10e32-de23-4d5c-8fbc-24b002a3e54a","body_text":"Publication: Histone deacetylase inhibitors down-regulate G-protein-coupled estrogen receptor and the GPER-antagonist G-15 inhibits proliferation in endometriotic cells\nHistone deacetylase inhibitors down-regulate G-protein-coupled estrogen receptor and the GPER-antagonist G-15 inhibits proliferation in endometriotic cells\nDate\nDate\nDate\nCitations\nImesch, P., Samartzis, E. P., Dedes, K. J., Fink, D., & Fedier, A. (2013). Histone deacetylase inhibitors down-regulate G-protein-coupled estrogen receptor and the GPER-antagonist G-15 inhibits proliferation in endometriotic cells. Fertility and Sterility, 100, 770–776. https://doi.org/10.1016/j.fertnstert.2013.05.008\nAbstract\nAbstract\nAbstract\nOBJECTIVE: To investigate whether histone deacetylase inhibitors reduce the expression of the G-protein-coupled estrogen receptor (GPER) and whether the functional inhibition of GPER by the antagonist G-15 decreases the proliferation of endometriotic cells. DESIGN: In vitro study. SETTING: University hospital. PATIENT(S): Immortalized epithelial endometriotic cells. INTERVENTION(S): Treatment with the histone deacetylase inhibitor romidepsin or suberoylanilide hydroxamic acid (SAHA), or with the GPER antagonist G-15. MAIN OUTCOME\nMetrics\nViews\nAdditional indexing\nCreators (Authors)\nVolume\nVolume\nVolume\nNumber\nNumber\nNumber\nPage range/Item number\nPage range/Item number\nPage range/Item number\nPage end\nPage end\nPage end\nItem Type\nItem Type\nItem Type\nIn collections\nDewey Decimal Classifikation\nDewey Decimal Classifikation\nDewey Decimal Classifikation\nLanguage\nLanguage\nLanguage\nPublication date\nPublication date\nPublication date\nDate available\nDate available\nDate available\nISSN or e-ISSN\nISSN or e-ISSN\nISSN or e-ISSN\nOA Status\nOA Status\nOA Status\nPublisher DOI\nMetrics\nViews\nCitations\nImesch, P., Samartzis, E. P., Dedes, K. J., Fink, D., & Fedier, A. (2013). Histone deacetylase inhibitors down-regulate G-protein-coupled estrogen receptor and the GPER-antagonist G-15 inhibits proliferation in endometriotic cells. Fertility and Sterility, 100, 770–776. https://doi.org/10.1016/j.fertnstert.2013.05.008","source_license":"CC0","license_restricted":false}