{"paper_id":"d621d89d-d468-4feb-a1ad-855bc9f8b4e4","body_text":"Psychoimmune interactions were studied in women of reproductive age with endometriosis. Pronounced immunological shifts manifested in a shift of the T-cellular immunity, resulting in imbalanced production of pro- (IL-1β, IL-2, IFN-γ) and anti-inflammatory (IL-4) cytokines. Significant correlations between the severity of mental shifts and immunopathogenetic factors in the studied patient population demonstrated the psychoneuroimmune nature of endometriosis.\nSimilar content being viewed by others\nReferences\nE. K. Ailamazyan, M. I. Yarmolinskaya, N. Yu. Shved, et al., Vestn. Rossiisk. Voen. Med. Akad., No. 2, 16–22 (2009).\nYu. A. Aleksandrovskii and V. P. Chekhonin, Clinical Immunology of Borderline Mental Disorders [in Russian], Moscow (2005).\nV. P. Baskakov, Yu. V. Tsvelev, and E. F. Kira, The Endometrioid Disease [in Russian], St. Petersburg (2002).\nG. N. Kryzhanovskii, S. V. Magaeva, S. V. Makarov, et al., Neuroimmunopathology [in Russian], Moscow (2003).\nD. M. Mendelevich and V. D. Mendelevich, Nevrol. Vestn., 25, Nos. 1–2, 104–108 (1993).\nPsychotherapeutic Encyclopedia, Ed. B. D. Karvasarskii [in Russian], St. Petersburg (1998).\nV. Ya. Semke, E. D. Schastnyi, and G. G. Simutkin, Affective Disorders [in Russian], Tomsk (2004).\nH. O. Besedovsky and A. D. Rey, Brain Behav. Immun., 21, No. 1, 33–44 (2007).\nR. Dantzer, Ibid., 15, No. 1, 7–24 (2001).\nM. R. Irwin, Ibid., 22, No. 2, 129–139 (2008).\nM. R. Irwin and A. H. Miller, Ibid., 21, No. 4, 374–383 (2007).\nG. Jones, C. Jenkinson, N. Taylor, et al., Hum. Reprod., 21, No. 10, 2686–2693 (2006).\nD. Kerr, C. Krishnan, M. L. Pucak, and J. Carmen, Int. Rev. Psychiatry, 17, No. 6, 443–449 (2005).\nE. L. Poleshuk, M. J. Bair, K. Kroenke, et al., Psychosomatics, 50, No. 3, 270–276 (2009).\nM. Rauchfuss, H. Kentenich, F. Siedentopf, and G. Danzer, J. Psychosom. Obstet. Gynaecol., 26, No. 2, 85–91 (2005).\nF. Siedentopf, N. Tariverdian, M. Rucke, et al., Am. J. Reprod. Immunol., 60, No. 5, 449–461 (2008).\nAuthor information\nAuthors and Affiliations\nCorresponding author\nAdditional information\nTranslated from Byulleten’ Eksperimental’noi Biologii i Meditsiny, Vol. 152, No. 7, pp. 100–105, July, 2011\nRights and permissions\nAbout this article\nCite this article\nNasyrova, R.F., Sotnikova, L.S., Baystrukova, N.V. et al. Psychoimmune Interactions in Women of Reproductive Age with Endometriosis. Bull Exp Biol Med 152, 93–97 (2011). https://doi.org/10.1007/s10517-011-1463-0\nReceived:\nPublished:\nIssue date:\nDOI: https://doi.org/10.1007/s10517-011-1463-0","source_license":"CC0","license_restricted":false}