{"paper_id":"d4679b53-c3f1-45c0-b1e3-f6804d4820bb","body_text":"Abstract\nBackground\nOvarian endometriosis is the most frequent type of endometriosis. Despite the use of surgery and medication, many patients suffer from recurrence within near future. Currently, there are no effective clinical characteristics available to predict the time to recurrence in ovarian endometriosis patients.\nPurpose\nTo identify the effective clinical indicators for early and late endometrioma recurrence, we compared the clinical characteristics of early and late recurrence after treatment.\nMethods\nWe collected 358 patients with ovarian endometriosis who had a minimum of 5 years of postoperative follow-up after undergoing a laparoscopic excision of ovarian endometrioma performed at Peking Union Medical College Hospital from January 2009 to April 2013.\nResults\nA total of 358 patients were recruited in the validation set, with a median follow-up time of 83 months (60–120 months). Till the last follow-up, 68 patients exhibited recurrence. Three-year and 5-year recurrence rates were 9.2% and 15.4%, respectively. Univariate analysis in our study showed that patient with endometrioma surgery history had higher incidence of recurrence in 3 years after re-surgery (OR: 5.594, P = 0.029). Univariate and multivariate analyses using the logistic regression showed that the presence of tenesmus before surgery affected the incidence of early recurrence with a ratio of 57.9% (11/19) and 89.5% (17/19) in 3 years and 5 years after surgery, respectively.\nConclusions\nPresence of tenesmus before surgery may be linked to the early recurrence of endometrioma.\nSimilar content being viewed by others\nAvailability of data and materials\nThe dataset supporting the conclusions of this article is included within the article and its additional files.\nAbbreviations\n- ART:\n-\nArtificial reproduction technology\n- ASRM:\n-\nAmerican Society for Reproductive Medicine\n- BMI:\n-\nBody mass index\n- CA-125:\n-\nCarbohydrate antigen 125\n- CI:\n-\nConfidence interval\n- DIE:\n-\nDeep invasive endometriosis\n- GnRHa:\n-\nGonadotropin-releasing hormone agonist\n- OR:\n-\nOdds ratio\n- QoL:\n-\nQuality of life\n- TTR:\n-\nTime to recurrence\n- VAS:\n-\nVisual analog scale\nReferences\nChapron C, Boucher E, Fauconnier A, Vieira M, Dubuisson JB, Vacher-Lavenu MC (2002) Anatomopathological lesions of bladder endometriosis are heterogeneous. 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J Minim Invasive Gynecol 25(5):786–793. https://doi.org/10.1016/j.jmig.2017.12.025\nAcknowledgments\nNone.\nFunding\nOur work was supported by the National Key R&D Program of China (No. 2017YFC1001200), National Natural Science Foundation of China (No. 81501237), and 2016 PUMCH Science Fund for Junior Faculty (No. PUMCH-2016-2.2).\nAuthor information\nAuthors and Affiliations\nContributions\nJL: study conception and design. XL: manuscript writing. WZ: data analysis. XC, YD, JS: data collection. SJ, SC, YW: pathological investigation. The manuscript has been read and approved by all the authors. The requirements for authorship have been met. Each author believes that the manuscript represents honest work.\nCorresponding author\nEthics declarations\nConflicts of interest\nThe authors declare that they have no conflict of interests.\nCode availability\nNot applicable.\nEthics approval and consent to participate\nThis study was approved by the Ethics Committee of Peking Union Medical College Hospital.\nAdditional information\nPublisher's Note\nSpringer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.\nRights and permissions\nAbout this article\nCite this article\nLi, X., Zhang, W., Chao, X. et al. Clinical characteristics difference between early and late recurrence of ovarian endometriosis after laparoscopic cystectomy. Arch Gynecol Obstet 302, 905–913 (2020). https://doi.org/10.1007/s00404-020-05657-5\nReceived:\nAccepted:\nPublished:\nVersion of record:\nIssue date:\nDOI: https://doi.org/10.1007/s00404-020-05657-5","source_license":"CC0","license_restricted":false}