{"paper_id":"d31d8fb4-183a-4165-9d29-de2c0657c6c8","body_text":"Abstract\nThe gynaecological impact of PoTS is associated with hypermobile Ehlers Danlos syndrome (hEDS), mast cell activation syndrome (MCAS), histamine intolerance and the influence of female sex hormones. The menstrual cycle plays a key role in changing the cardiovascular environment as well producing inflammatory episodes during menstruation. Women with PoTS have more menstrual irregularities and also suffer from pelvic pain, and vulval inflammatory and pain conditions. Treatment can involve suppressing the menstrual cycle hormonally or using type 1 and 2 histamine receptor blockers or mast cell stabilising medications. 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In: Gall, N., Kavi, L., Lobo, M.D. (eds) Postural Tachycardia Syndrome. Springer, Cham. https://doi.org/10.1007/978-3-030-54165-1_18\nDownload citation\nDOI: https://doi.org/10.1007/978-3-030-54165-1_18\nPublished:\nPublisher Name: Springer, Cham\nPrint ISBN: 978-3-030-54164-4\nOnline ISBN: 978-3-030-54165-1\neBook Packages: MedicineMedicine (R0)","source_license":"CC0","license_restricted":false}