{"paper_id":"d2bad846-8cf4-4469-9ac8-641bd53b78dd","body_text":"EXPRESSION OF CONCERN: Melatonin Protects Against Endometriosis via Regulation of Matrix Metalloproteinase-3 and an Apoptotic Pathway\nAbstract\nEXPRESSION OF CONCERN: S. Paul, P. Bhattacharya, P. D. Mahapatra, and S. Swarnakar, “Melatonin Protects Against Endometriosis via Regulation of Matrix Metalloproteinase-3 and an Apoptotic Pathway,” Journal of Pineal Research 49, no. 2 (2010): 156–168, https://doi.org/10.1111/j.1600-079X.2010.00780.x.\nThis Expression of Concern is for the above article, published online on 02 August 2010 in Wiley Online Library (wileyonlinelibrary.com), and has been issued by agreement between the journal Editor-in-Chief, Gianluca Tosini; and John Wiley & Sons Ltd. The Expression of Concern has been agreed due to concerns raised by third parties. Specifically, the features of the sections presented in Figure 6 (A), (B), and (C) were found to closely resemble those of small intestine rather than endometrial (uterine) tissue in mice. Due to the time elapsed since publication, the authors were unable to retrieve the raw data underlying the images. Despite the authors highlighting several features in their clarification to support that the images represent uterine tissue from a surgically induced mouse endometriosis model—such as morphological details of uterine glands, stroma, blood vessels, and expected cycle-related changes—they also acknowledge that the possibility of having reported a different tissue type cannot be fully ruled out. Therefore, the journal has decided to issue an Expression of Concern to inform and alert the readers.","source_license":"public-domain-us","license_restricted":false}