{"paper_id":"c25376d8-20d4-4bb8-b125-d87da173863c","body_text":"Zusammenfassung\nDie Adenomyose resultiert aus der Invasion des basalen Endometriums in das umgebende Myometrium (Bazot et al. 2001) und stellt damit eine Erkrankung der sog. Archimetra dar, die aus dem Endometrium selbst sowie dem subendometrialen Endometrium (= Archimyometrium = Junktionalzone) besteht (Bazot et al. 2001; Leyendecker et al. 2002). Die Adenomyosis uteri stellt sich im MRT als hypodense verbreiterte Junktionalzone insbesondere an der Uterushinterwand dar (Kunz et al. 2007).\nAccess this chapter\nTax calculation will be finalised at checkout\nPurchases are for personal use only\nPreview\nUnable to display preview. Download preview PDF.\nSimilar content being viewed by others\nLiteratur\nAbou-Setta AM, Al-Inany HG, Farquhar CM (2006) Levonorgestrel-releasing intrauterine device (LNG-IUD) for symptomatic endometriosis following surgery. Cochrane Database Syst Rev 4: CD005072\nAllen C, Hopewell S, Prentice A, Gregory D (2009) Nonsteroidal antiinflammatory drugs for pain in women with endometriosis. Cochrane Database Syst Rev 15: CD004753\nBazot M, Cortez A, Darai E, Rouger J, Chopier J, Antoine JM, Uzan S (2001) Ultrasonography compared with magnetic resonance imaging for the diagnosis of adenomyosis: correlation with histopathology. Hum Reprod 16: 2427–2433\nBazot M, Daraï E, Rouger J, Detchev R, Cortez A, Uzan S (2002) Limitations of transvaginal sonography for the diagnosis of adenomyosis, with histopathological correlation. Ultrasound Obstet Gynecol 20: 605–611\nBragheto AM, Caserta N, Bahamondes L, Petta CA (2007) Effectiveness of the levonorgestrel-releasing intrauterine system in the treatment of adenomyosis diagnosed and monitored by magnetic resonance imaging. Contraception 76: 195–9\nBratby MJ, Walker WJ (2009) Uterine artery embolisation for symptomatic adenomyosis – mid-term results. Eur J Radiol 70: 128–132\nBrown J, Pan A, Hart RJ (2010) Gonadotrophin-releasing hormone analogues for pain associated with endometriosis. Cochrane Database Syst Rev 8: CD008475\nChampaneria R, Abedin P, Daniels J, Balogun M, Khan KS (2010) Ultrasound scan and magnetic resonance imaging for the diagnosis of adenomyosis: systematic review comparing test accuracy. Acta Obstet Gynecol Scand 89: 1374–1384\nCho S, Nam A, Kim H, Chay D, Park K, Cho DJ, Park Y, Lee B (2008) Clinical effects of the levonorgestrel-releasing intrauterine device in patients with adenomyosis. Am J Obstet Gynecol 198: 373. e1–7\nCirpan T, Yeniel O, Ulukus M, Ozbal A, Gundem G, Ozsener S, Mete Itil I, Zekioglu O (2008) Clinical symptoms and histopathological findings in subjects with adenomyosis uteri. Clin Exp Obstet Gynecol 35: 48–53\nDavis L, Kennedy SS, Moore J, Prentice A (2007) Modern combined oral contraceptives for pain associated with endometriosis. Cochrane Database Syst Rev 18: CD001019\nDong X, Yang Z (2010) High-intensity focused ultrasound ablation of uterine localized adenomyosis. Curr Opin Obstet Gynecol 22: 326–330\nDueholm M (2006) Transvaginal ultrasound for diagnosis of adenomyosis: a review. Best Pract Res Clin Obstet Gynaecol 20: 569–582\nDueholm M, Lundorf E (2007) Transvaginal ultrasound or MRI for diagnosis of adenomyosis. Curr Opin Obstet Gynecol 19: 505–512\nFedele L, Bianchi S, Frontino G (2008) Hormonal treatments for adenomyosis. Best Pract Res Clin Obstet Gynaecol 22: 333–339\nGordts S, Brosens JJ, Fusi L, Benagiano G, Brosens I (2008) Uterine adenomyosis: a need for uniform terminology and consensus classification. Reprod Biomed Online 17: 244–248\nHarada T, Momoeda M, Taketani Y, Aso T, Fukunaga M, Hagino H, Terakawa N (2009) Dienogest is as effective as intranasal buserelin acetate for the relief of pain symptoms associated with endometriosis– a randomized, double-blind, multicenter, controlled trial. Fertil Steril 91: 675–681\nJeng CJ, Huang SH, Shen J, Chou CS, Tzeng CR (2007) Laparoscopyguided myometrial biopsy in the definite diagnosis of diffuse adenomyosis. Hum Reprod 22: 2016–9\nJuang CM, Chou P, Yen MS, Twu NF, Horng HC, Hsu WL (2007a) Primary dysmenorrhea and risk of preterm delivery. Am J Perinatol 24: 11–16\nJuang CM, Chou P, Yen MS, Twu NF, Horng HC, Hsu WL (2007b) Adenomyosis and risk of preterm delivery. BJOG 114: 165–169\nKim MD, Kim S, Kim NK, Lee MH, Ahn EH, Kim HJ, Cho JH, Cha SH (2007) Long-term results of uterine artery embolization for symptomatic adenomyosis. Am J Roentgenol 188: 176–181\nKimura F, Takahashi K, Takebayashi K, Fujiwara M, Kita N, Noda Y, Harada N (2007) Concomitant treatment of severe uterine adenomyosis in a premenopausal woman with an aromatase inhibitor and a gonadotropin-releasing hormone agonist. Fertil Steril 87: 1468.e9–12\nKissler S, Zangos S, Wiegratz I, Kohl J, Rody A, Gaetje R, Doebert N, Wildt L, Kunz G, Leyendecker G, Kaufmann M (2007) Utero-tubal sperm transport and its impairment in endometriosis and adenomyosis. Ann N Y Acad Sci 1101: 38–48\nKissler S, Zangos S, Kohl J, Wiegratz I, Rody A, Gätje R, Vogl TJ, Kunz G, Leyendecker G, Kaufmann M (2008) Duration of dysmenorrhea and extent of adenomyosis visualised by magnetic resonance imaging. Eur J Obstet Gynecol Reprod Biol 137: 204–209\nKunz G, Beil D, Huppert P, Noe M, Kissler S, Leyendecker G (2005) Adenomyosis in endometriosis – prevalence and impact on fertility. Evidence from magnetic resonance imaging. Hum Reprod 20: 2309–2316\nKunz G, Herbertz M, Beil D, Huppert P, Leyendecker G (2007) Adenomyosis as a disorder of the early and late human reproductive period. Reprod Biomed Online 15: 681–685\nLeyendecker G, Herbertz M, Kunz G, Mall G (2002) Endometriosis results from the dislocation of basal endometrium. Hum Reprod 17: 2725–2736\nMolinas CR, Campo R (2006) Office hysteroscopy and adenomyosis. Best Pract Res Clin Obstet Gynaecol 20: 557–67\nOsada H, Silber S, Kakinuma T, Nagaishi M, Kato K, Kato O (2011) Surgical procedure to conserve the uterus for future pregnancy in patients suffering from massive adenomyosis. Reprod Biomed Online 22: 94–99\nParazzini F, Vercellini P, Panazza S, Chatenoud L, Oldani S, Croisignani PG (1997) Risk factors for ademyosis. Hum Reprod 12: 1275–1279\nParazzini F, Mais V, Cipriani S, Busacca M, Venturini P; GISE (2009) Determinants of adenomyosis in women who underwent hysterectomy for benign gynecological conditions: results from a prospective multicentric study in Italy. Eur J Obstet Gynecol Reprod Biol 143: 103–106\nParker JD, Leondires M, Sinaii N, Premkumar A, Nieman LK, Stratton P (2006) Persistence of dysmenorrhea and nonmenstrual pain after optimal endometriosis surgery may indicate adenomyosis. Fertil Steril 86: 711–715\nPeric H, Fraser IS (2006) The symptomatology of adenomyosis. Best Pract Res Clin Obstet Gynaecol 20: 547–555Prentice A, Deary AJ, Bland E (2000) Progestagens and anti-progestagens for pain associated with endometriosis. Cochrane Database Syst Rev 2: CD002122\nRabinovici J, Inbar Y, Eylon SC, Schiff E, Hananel A, Freundlich D (2006) Pregnancy and live birth after focused ultrasound surgery for symptomatic focal adenomyosis: a case report. Hum Reprod 21: 1255–1259\nReinhold C, McCarthy S, Bret PM, Mehio A, Atri M, Zakarian R, Glaude Y, Liang L, Seymour RJ (1996) Diffuse adenomyosis: comparison of endovaginal US and MR imaging with histopathologic correlation. Radiology 199: 151–158\nSammour A, Pirwany I, Usubutun A, Arseneau J, Tulandi T (2002) Correlations between extent and spread of adenomyosis and clinical symptoms. Gynecol Obstet Invest 54: 213–216\nSelak V, Farquhar C, Prentice A, Singla A (2007) Danazol for pelvic pain associated with endometriosis. Cochrane Database Syst Rev 17: CD000068\nSheng J, Zhang WY, Zhang JP, Lu D (2009) The LNG-IUS study on adenomyosis: a 3-year follow-up study on the efficacy and side effects of the use of levonorgestrel intrauterine system for the treatment of dysmenorrhea associated with adenomyosis. Contraception 79: 189–193\nStrowitzki T, Faustmann T, Gerlinger C, Seitz C (2010a) Dienogest in the treatment of endometriosis-associated pelvic pain: a 12-week, randomized, double-blind, placebo-controlled study. Eur J Obstet Gynecol Reprod Biol 151: 193–198\nStrowitzki T, Marr J, Gerlinger C, Faustmann T, Seitz C (2010b) Dienogest is as effective as leuprolide acetate in treating the painful symptoms of endometriosis: a 24-week, randomized, multicentre, open-label trial. Hum Reprod 25: 633–641\nTempleman C, Marshall SF, Ursin G, Horn-Ross PL, Clarke CA, Allen M, Deapen D, Ziogas A, Reynolds P, Cress R, Anton-Culver H, West D, Ross RK, Bernstein L (2008) Adenomyosis and endometriosis in the California Teachers Study. Fertil Steril 90: 415–424\nTocci A, Greco E, Ubaldi FM (2008) Adenomyosis and ‘endometrialsubendometrial myometrium unit disruption disease’ are two different entities. Reprod Biomed Online 17: 281–291\nWada S, Kudo M, Minakami H (2006) Spontaneous uterine rupture of a twin pregnancy after a laparoscopic adenomyomectomy: a case report. J Minim Invasiv Gynecol 13: 166–168\nWeiss G, Maseelall P, Schott LL, Brockwell SE, Schocken M, Johnston JM (2009) Adenomyosis a variant, not a disease? Evidence from hysterectomized menopausal women in the Study of Women’s Health Across the Nation (SWAN). Fertil Steril 91: 201–206\nYang Z, Cao YD, Hu LN, Wang ZB (2009) Feasibility of laparoscopic high-intensity focused ultrasound treatment for patients with uterine localized adenomyosis. Fertil Steril 91: 2338–2343\nYeniel O, Cirpan T, Ulukus M, Ozbal A, Gundem G, Ozsener S, Zekioglu O, Yilmaz H (2007) Adenomyosis: prevalence, risk factors, symptoms and clinical findings. Clin Exp Obstet Gynecol 34: 163–167\nYoon SW, Kim KA, Cha SH, Kim YM, Lee C, Na YJ, Kim SJ (2008) Successful use of magnetic resonance-guided focused ultrasound surgery to relieve symptoms in a patient with symptomatic focal adenomyosis. Fertil Steril 90: 2018.e13–15\nZacharia TT, O’Neill MJ (2006) Prevalence and distribution of adnexal findings suggesting endometriosis in patients with MR diagnosis of adenomyosis. Br J Radiol 79: 303–307\nZaloudek C, Norris HJ Mesenchymal tumors of the uterus. In: Kurmann RJ, ed. Blaunstein´s Pathology of the Female Genital Tract. 3rd ed. New York, NY: Springer-Verlag 1987: 374\nZhang X, Yuan H, Deng L, Hu F, Ma J, Lin J (2008) Evaluation of the efficacy of a danazol-loaded intrauterine contraceptive device on adenomyosis in an ICR mouse model. Hum Reprod 23: 2024–2030\nAuthor information\nAuthors and Affiliations\nEditor information\nEditors and Affiliations\nRights and permissions\nCopyright information\n© 2013 Springer-Verlag Berlin Heidelberg\nAbout this chapter\nCite this chapter\nNawroth, F. (2013). Adenomyosis. In: Diedrich, K., Ludwig, M., Griesinger, G. (eds) Reproduktionsmedizin. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-30181-0_32\nDownload citation\nDOI: https://doi.org/10.1007/978-3-642-30181-0_32\nPublisher Name: Springer, Berlin, Heidelberg\nPrint ISBN: 978-3-642-30180-3\nOnline ISBN: 978-3-642-30181-0\neBook Packages: Medicine (German Language)","source_license":"CC0","license_restricted":false}