{"paper_id":"bffb1d03-08e4-4edb-bb39-03de707a2a4e","body_text":"Review Article\nEndometriosis: abnormal endometrium and dysfunctional immune response\n- Donald P. Braun\n- W. Paul Dmowski\nCurrent Opinion in Obstetrics & Gynecology 10(5):p 365-369, October 1998.\nThis review highlights recent studies that illuminate the role of the immune system in endometriosis. The findings are discussed in the framework of a model which proposes that endometriosis reflects an immunological selection process. Endometrial cells, which are inherently resistant to apoptosis and immune-mediated elimination, acquire the capacity to utilize the products of an activated immune sytem to establish ectopic foci of disease. Cyclical inflammatory/immune cell stimulation that fails to eliminate ectopic endometrial implants results in progressive immunological derangement and associated pathophysiological changes which are characteristic of the disease.\nCopyright © 1998 Lippincott Williams & Wilkins, Inc.","source_license":"CC0","license_restricted":false}