{"paper_id":"bfe68640-a264-40ab-a5a4-cff461ea303d","body_text":"Vol.:(0123456789)1 3\nArchives of Gynecology and Obstetrics (2020) 302:1559 \nhttps://doi.org/10.1007/s00404-020-05488-4\nCORRESPONDENCE\nComment on “Mucin gene polymorphisms are associated \nwith endometriosis in Korean women”\nSora Yasri1 · Viroj Wiwanitkit2\nReceived: 21 December 2019 / Accepted: 26 February 2020 / Published online: 9 March 2020 \n© Springer-Verlag GmbH Germany, part of Springer Nature 2020\nDear Editor,\nWe read the publication on “Mucin (MUC) gene polymor -\nphisms are associated with endometriosis in Korean women” \nwith a great interest [1 ]. Kim et al. concluded that “The \nMUC1 genotype may not be correlated with endometriosis \nsusceptibility. However, MUC4 polymorphisms are associ-\nated with the risk for endometriosis in Korean women [1].” \nIn fact, the single-nucleotide polymorphism (SNP) of MUC \nresults in molecular change, and the molecular change fur -\nther results in the alteration of phenotypic expression. This \nchange in, due to either, MUC1 or MUC4 SNPs should \naffect the final phenotypic expression. Nevertheless, Kim \net al. focused on only MUC1 and MUC4 SNPs. There are \nalso other genetic polymorphisms that might associate with \nendometriosis [2 ]. The examples of those genetic poly -\nmorphisms are tumor necrosis factor-α gene-1031T/C pro-\nmoter, vitamin D-binding protein and Interleukin 1 alpha \npolymorphisms [3, 4]. The effects of other possible genetic \nconfounding factors should be assessed in the future studies.\nCompliance with ethical standards \nConflict of interest The authors declare no conflict of interest.\nReferences\n 1. Kim JH, Kim TH, Kim YS, Jang WC, Ryu A, Hwang JY, Lee \nHH (2019) Mucin gene polymorphisms are associated with endo-\nmetriosis in Korean women. Arch Gynecol Obstet. https ://doi.\norg/10.1007/s0040 4-019-05409 -0 (Epub ahead of print)\n 2. Méar L, Herr M, Fauconnier A, Pineau C, Vialard F (2019) Poly-\nmorphisms and endometriosis: a systematic review and meta-\nanalyses. Hum Reprod Update. https ://doi.org/10.1093/humup d/\ndmz03 4 (Epub ahead of print)\n 3. Drakou A, Mavrogianni D, Ntzeros K, Protopapas A, Drakakis P, \nLoutradis D (2019) Association between tumor necrosis factor-α \ngene-1031T/C promoter polymorphism and endometriosis in a \nEuropean population. Horm Mol Biol Clin Investig. https ://doi.\norg/10.1515/hmbci -2019-0033\n 4. Cho MC, Kim JH, Jung MH, Cho IA, Jo HC, Shin JK, Lee SA, \nChoi WJ, Lee JH (2019) Analysis of vitamin D-binding protein \n(VDBP) gene polymorphisms in Korean women with and without \nendometriosis. Clin Exp Reprod Med 46(3):132–139\n 5. Badie A, Saliminejad K, Salahshourifar I, Khorram Khorshid \nHR (2019) Interleukin 1 alpha (IL1A) polymorphisms and risk \nof endometriosis in Iranian population: a case–control study. \nGynecol Endocrinol 28:1–4\nPublisher’s Note Springer Nature remains neutral with regard to \njurisdictional claims in published maps and institutional affiliations.\nSora Yasri and Viroj Wiwanitkit contributed equally.\nThis comment refers to the article available online at https ://doi.\norg/10.1007/s0040 4-019-05409 -0.\n * Sora Yasri \n sorayasri@Outlook.co.th\n1 KMT Primary Care Center, Bangkok, Thailand\n2 Dr DY Patil University, Pune, India","source_license":"CC0","license_restricted":false}