{"paper_id":"bb2385f6-0ba3-4df0-8600-ccfa15cd8b4e","body_text":"Clear Cell Adenocarcinoma Arising in Endometriosis of a Previous Episiotomy Site\n- Yong-Soon Kwon\n- Joo-Hyun Nam\n- Gawon Choi\nBACKGROUND:\nMalignant transformation of endometriosis in an episiotomy site is rare.\nCASE:\nA 42-year-old woman presented with a palpable mass, 2.5 cm in size, just inside the posterior commissure of the vagina, at the site of a previous episiotomy for a vaginal delivery. Three years previously, an endometriotic cyst had been excised at the same site, and the patient had been treated with a gonadotropin-releasing hormone analogue for 6 months. Biopsy revealed a clear cell adenocarcinoma arising in endometriosis. The patient underwent radical surgery alone without adjuvant therapy. At 10-month follow-up, there was no evidence of recurrence.\nCONCLUSION:\nPatients who experience a recurrence of extragonadal endometriosis after prior therapy should be monitored carefully for malignant degeneration.","source_license":"public-domain-us","license_restricted":false}