{"paper_id":"b2f3579f-12b0-4982-b064-c0b8186a4d8b","body_text":"Abstract\nIt has been recognized for many years that the perimenopause is a phase during which the menstrual pattern may become increasingly variable and erratic as ovarian function gears down to a low level. Variations in the menstrual pattern at this stage of life have substantial implications because they are an important indicator to individual women of the approach of a major life change. Indeed, the cessation of menses is the event that defines the occurrence of menopause — “the last natural menstrual period which a woman experiences” — an event that can be determined only in retrospect.\nPreview\nUnable to display preview. Download preview PDF.\nSimilar content being viewed by others\nReferences\nRichardson SJ, Senikas V, Nelson JF. Follicular depletion during the menopausal transition: evidence for accelerated loss and ultimate exhaustion. 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Clinical manifestations and end-organ effects associated with abnormal gonadotropin release. Clin Obstet Gynaecol 1976;3:591–614.\nSmith SK, Abel MH, Kelly RW, Baird DT. The synthesis of prostaglandins from persistent proliferative endometrium. J Clin Endocrinol Metab 1982; 55:284–9.\nEditor information\nEditors and Affiliations\nRights and permissions\nCopyright information\n© 1997 Springer-Verlarg New York, Inc.\nAbout this chapter\nCite this chapter\nFraser, I.S. (1997). Menstrual Changes During the Perimenopause. In: Lobo, R.A. (eds) Perimenopause. Serono Symposia USA. Springer, New York, NY. https://doi.org/10.1007/978-1-4612-2288-0_17\nDownload citation\nDOI: https://doi.org/10.1007/978-1-4612-2288-0_17\nPublisher Name: Springer, New York, NY\nPrint ISBN: 978-1-4612-7488-9\nOnline ISBN: 978-1-4612-2288-0\neBook Packages: Springer Book Archive\nKeywords\n- Menstrual Bleeding\n- Menstrual Blood Loss\n- Acta Obstet Gynecol\n- Dysfunctional Uterine Bleeding\n- Menstrual Pattern\nThese keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.","source_license":"CC0","license_restricted":false}