{"paper_id":"accbd6ec-136b-4304-9d3a-9670f9c534bf","body_text":"Abstract\nObjective\nTo investigate the effect of Chinese medicine (CM) and Western medicine (WM) on quality of life (QOL) after conservative surgery for endometriosis.\nMethods\nA total of 320 patients with endometriosis were randomized into two groups by using random block design, CM group (160 cases, activating blood circulation and removing blood stasis treatment based on syndrome differentiation) and WM group (160 cases, gonadotropin-releasing hormone agonist or gestrinone treatment) after conservative surgery. Treatment was given for 3–6 months (according to the revised American Fertility Society scoring system stage), and the World Health Organization QOL-BREF (WHOQOL-BREF) was applied to patients before and after treatment to assess QOL.\nResults\nThere were 136 cases in the CM group and 141 cases in the WM group completing therapy. In the CM group, the use of the WHOQOL-BREF showed that the physical, psychological and environmental scores posttreatment were significantly higher than those at pre-treatment (P<0.05), and for 12 items (pain and discomfort, energy and fatigue, sleep and rest, mobility, activities of daily living, work capacity, negative feelings, health and social care: accessibility and quality, participation in and opportunities for recreation/leisure activities, appetite, QOL score, overall health status and QOL), the difference in scores was significant (P<0.05). In the WM group, 4 items (pain and discomfort, opportunities for acquiring new information and skills, QOL score, overall health status and QOL) had significantly different scores post-treatment compared with those at pre-treatment (P<0.05). Before treatment, the QOL in the two groups of patients showed no significant difference (P>0.05). After treatment, the scores for physical health in the CM group were significantly higher than those of the WM group (P<0.05) and the scores of 4 items (mobility, activities of daily living, sexual activity, QOL score) in the CM group were significantly higher than those in the WM group (P<0.05).\nConclusions\nCM and WM treatment could improve the QOL of patients with endometriosis after conservative surgery. CM treatment is more effective than WM.\nSimilar content being viewed by others\nReferences\nEndometriosis Group, Special Committee of Obstetrics and Gynecology, Chinese Medical Association. Endometriosis diagnosis and treatment guidelines. Chin J Obstetr Gynecol (Chin) 2007;42:645–648.\nCao ZY. Chinese obstetrics and gynecology. 2nd ed. Beijing: People’s Medical Publishing House; 2004:1265.\nMinistry of Health of the People’s Republic of China. Guidelines for clinical research of new drugs of traditional Chinese medicine. 1st ed. 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An introduction to study on quality of life and measurement scales. Modern Rehabil (Chin) 2000;4:1127–1129,1145.\nHao YT, Fanc JQ, Power MJ, Wu SM, Zhu SM. The equivalence of WHOQOL-BREF among 13 culture versions. Chin Ment Health J (Chin) 2006;2:71–75.\nAuthor information\nAuthors and Affiliations\nCorresponding author\nAdditional information\nSupported by the “Eleventh-Five” National Technology Support Program Project (No. 2006BAI04A17)\nRights and permissions\nAbout this article\nCite this article\nZhao, Rh., Liu, Y., Tan, Y. et al. Chinese medicine improves postoperative quality of life in endometriosis patients: A randomized controlled trial. Chin. J. Integr. Med. 19, 15–21 (2013). https://doi.org/10.1007/s11655-012-1196-6\nReceived:\nPublished:\nIssue date:\nDOI: https://doi.org/10.1007/s11655-012-1196-6","source_license":"CC0","license_restricted":false}