{"paper_id":"acb0ac48-d63d-405d-b62e-49241b98af60","body_text":"Abstract\nPurpose\nTo investigate the hypothesis that surgical treatment of endometriosis in infertile patients may improve pregnancy rates by improving embryo quality.\nMethods\nWe conducted a retrospective evaluation of 30 infertile patients treated with in vitro fertilization (IVF) before and after surgery for endometriosis. Patients served as their own controls and only cycles with similar stimulation protocols were compared.\nResults\nUsing standard visual evaluation, embryo quality on day 3 was similar before and after surgical treatment of endometriosis. Fifty seven percent of patients had stage I–II endometriosis and 43% had stage III–IV disease. No patients had a live birth after the first IVF cycle and 43% of patients had a live birth with the IVF cycle after surgery.\nConclusions\nSurgical treatment of endometriosis does not alter embryo quality in patients with infertility treated with IVF.\nSimilar content being viewed by others\nReferences\nD’Hooghe TM, Debrock S, Hill JA, Meuleman C. Endometriosis and subfertility: is the relationship resolved? Semin Reprod Med 2003;21(2):243–54. doi:10.1055/s-2003-41330.\nBarnhart K, Dunsmoor-Su R, Coutifaris C. Effect of endometriosis on in vitro fertilization. Fertil Steril 2002;77(6):1148–55. doi:10.1016/S0015-0282(02)03112-6.\nKennedy S, Bergqvist A, Chapron C, D’Hooghe T, Dunselman G, Greb R. ESHRE special interest group for endometriosis and endometrium guideline development group. ESHRE guideline for the diagnosis and treatment of endometriosis. Hum Reprod 2005;20:2698–704. doi:10.1093/humrep/dei135.\nMarcoux S, Maheux R, Bérubé S. 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Gene expression analysis of endometrium reveals progesterone resistance and candidate susceptibility genes in women with endometriosis. Endocrinology 2007;148(8):3814–26. doi:10.1210/en.2006-1692.\nAuthor information\nAuthors and Affiliations\nCorresponding author\nAdditional information\nCapsule Surgical treatment of endometriosis did not alter embryo quality in patients undergoing in vitro fertilization.\nRights and permissions\nAbout this article\nCite this article\nShahine, L.K., Burney, R.O., Behr, B. et al. Embryo quality before and after surgical treatment of endometriosis in infertile patients. J Assist Reprod Genet 26, 69–73 (2009). https://doi.org/10.1007/s10815-008-9287-1\nReceived:\nAccepted:\nPublished:\nIssue date:\nDOI: https://doi.org/10.1007/s10815-008-9287-1","source_license":"CC0","license_restricted":false}