{"paper_id":"a91d3634-2293-4cd1-af1f-59f25538cc81","body_text":"RENDO™ CLINICAL PROTOCOL v3.0 Reproductive Endo-Neuro-Dynamic Optimization: an integrated pre-, intra- and post-surgical protocol for ovarian reserve preservation and fertility restoration after endometrioma excision\nAuthors/Creators\n- 1. Hudziak Academy\n- 2. Victoria Gudziak Fertility Management Center\nDescription\nOvarian endometrioma excision remains a double-edged intervention: it improves pelvic pain and ART access, yet bilateral or repeated stripping surgery is associated with measurable decline in anti-Müllerian hormone (AMH) and antral follicle count (AFC), a phenomenon conceptually framed by the author as surgical ovarian aging. Contemporary protocols address the surgical act itself but neglect the pre-operative metabolic window, the first 72 postoperative hours, and the neuro-motivational dimension of the 12-month fertility trajectory, where attrition from ART programs reaches 25–40%.\nObjective. To describe and standardize RENDO™ (Reproductive Endo-Neuro-Dynamic Optimization), a six-module integrated protocol — PREP, SURG, RECOVER, MIND, DRIVE, TRACK — spanning 4–8 weeks before surgery to 12 months after, combining anti-adhesion excisional technique, targeted nutraceutical matrices, polyvagal-informed psychosomatic stabilization, dopamine-based behavioral architecture, and a digital companion with composite outcome indices.\nMethods. Single-arm prospective implementation; eligibility per ICD-10 N80.1–N80.3 / ICD-11 GA10.Z–GA10.3; primary endpoint: relative AMH change at 3 months; secondary endpoints: AFC recovery ratio, Ovarian Shock Index (OSI) at post-op day 3, RENDO™ Score (0–100), RPS-SCORE dynamics, ART attrition rate.\nConclusion. RENDO™ reframes post-endometrioma care from a passive convalescence model to an active, measurable, patient-facing recovery system.\nFiles\nRENDO_Clinical_Protocol_v3.0_Hudziak_Viktoriya.pdf\nFiles\n(261.5 kB)\n| Name | Size | Download all |\n|---|---|---|\n|\nmd5:c306f02f0f48705adccfe40de0b64541\n|\n261.5 kB | Preview Download |","source_license":"CC0","license_restricted":false}