{"paper_id":"a1575a81-4e8b-42c8-b44c-734963f9d39e","body_text":"Case Reports: Case Report\nGeneral Anesthesia and Fabry Disease: A Case Report\n- Stefan Krüger*\n- Albina Nowak†\n- Torben Christoph Müller*\nFabry disease is an inherited X-linked disorder characterized by the absence (in men) or deficiency (in women) in α-galactosidase A activity that causes a progressive accumulation of glycosphingolipids within lysosomes of cells of all the major organ systems. The subsequent organ damage that manifests in childhood and early adulthood presents a widely variable clinical picture of pain, hypertension, and cardiac, renal, nervous system, and lung dysfunction. We present 2 female patients with Fabry disease who required general anesthesia twice for gynecological and trauma surgery, respectively, and discuss their perioperative management based on new information in the medical literature.\nCopyright © 2017 International Anesthesia Research Society","source_license":"public-domain-us","license_restricted":false}