{"paper_id":"a0b5c333-0019-486d-94fa-2403be5776f5","body_text":"Ultrasound characteristics of sarcoma in the uterine cervix: ‘ballet tutu’ sign\nL. Hovsepyan\nGlasbo Clinic, Center for Reproductive Health, Obstetrics and Gynecology, Yerevan, Armenia\nDepartment of Gynecology, Erebouni Medical Center, Yerevan, Armenia\nSearch for more papers by this authorA. Stepanyan\nDepartment of Gynecological Oncology, Nairi Medical Center, Yerevan, Armenia\nSearch for more papers by this authorA. Saradyan\nDepartment of Pathology, Davidyants Laboratories, Yerevan, Armenia\nSearch for more papers by this authorN. Asilbekyan\nGlasbo Clinic, Center for Reproductive Health, Obstetrics and Gynecology, Yerevan, Armenia\nSearch for more papers by this authorS. Tevosyan\nGlasbo Clinic, Center for Reproductive Health, Obstetrics and Gynecology, Yerevan, Armenia\nSearch for more papers by this authorI. Mazmanian\nGlasbo Clinic, Center for Reproductive Health, Obstetrics and Gynecology, Yerevan, Armenia\nSearch for more papers by this authorG. Tonyan\nGlasbo Clinic, Center for Reproductive Health, Obstetrics and Gynecology, Yerevan, Armenia\nSearch for more papers by this authorA. Mirzoyan\nDepartment of Gynecology, Erebouni Medical Center, Yerevan, Armenia\nSearch for more papers by this authorCorresponding Author\nL. Valentin\nDepartment of Clinical Sciences Malmö, Lund University, Malmö, Sweden\nDepartment of Obstetrics and Gynecology, Skane University Hospital, Malmö, Sweden\nCorrespondence. (e-mail: [email protected])\nSearch for more papers by this authorL. Hovsepyan\nGlasbo Clinic, Center for Reproductive Health, Obstetrics and Gynecology, Yerevan, Armenia\nDepartment of Gynecology, Erebouni Medical Center, Yerevan, Armenia\nSearch for more papers by this authorA. Stepanyan\nDepartment of Gynecological Oncology, Nairi Medical Center, Yerevan, Armenia\nSearch for more papers by this authorA. Saradyan\nDepartment of Pathology, Davidyants Laboratories, Yerevan, Armenia\nSearch for more papers by this authorN. Asilbekyan\nGlasbo Clinic, Center for Reproductive Health, Obstetrics and Gynecology, Yerevan, Armenia\nSearch for more papers by this authorS. Tevosyan\nGlasbo Clinic, Center for Reproductive Health, Obstetrics and Gynecology, Yerevan, Armenia\nSearch for more papers by this authorI. Mazmanian\nGlasbo Clinic, Center for Reproductive Health, Obstetrics and Gynecology, Yerevan, Armenia\nSearch for more papers by this authorG. Tonyan\nGlasbo Clinic, Center for Reproductive Health, Obstetrics and Gynecology, Yerevan, Armenia\nSearch for more papers by this authorA. Mirzoyan\nDepartment of Gynecology, Erebouni Medical Center, Yerevan, Armenia\nSearch for more papers by this authorCorresponding Author\nL. Valentin\nDepartment of Clinical Sciences Malmö, Lund University, Malmö, Sweden\nDepartment of Obstetrics and Gynecology, Skane University Hospital, Malmö, Sweden\nCorrespondence. (e-mail: [email protected])\nSearch for more papers by this authorDATA AVAILABILITY STATEMENT\nThe data that support the findings of this study are available on request from the corresponding author. The data are not publicly available due to privacy or ethical restrictions.\nSupporting Information\n| Filename | Description |\n|---|---|\n| uog70103-sup-0001-Appendix.docxWord 2007 document , 21.7 KB |\nAppendix S1 Case reports of clinical and ultrasound characteristics of five cases of sarcoma in the uterine cervix. |\n| uog70103-sup-0002-FigureS1.pptxPowerPoint 2007 presentation , 6.3 MB |\nFigure S1 Ultrasound (a–c), macroscopic (d) and microscopic (e) images in Case 1, diagnosed as pleomorphic high-grade rhabdomyosarcoma, International Federation of Gynecology and Obstetrics Stage IB, in uterine cervix. |\n| uog70103-sup-0003-FigureS2.pptxPowerPoint 2007 presentation , 6.4 MB |\nFigure S2 Ultrasound (a–c), macroscopic (d) and microscopic (e) images in Case 2, diagnosed as leiomyosarcoma, International Federation of Gynecology and Obstetrics Stage IB, in uterine cervix. |\n| uog70103-sup-0004-FigureS3.pptxPowerPoint 2007 presentation , 8.7 MB |\nFigure S3 Ultrasound (a–c), macroscopic (d), microscopic (e) and fluorescence in situ hybridization assay (f) images in Case 4, diagnosed as neurotrophic tyrosine receptor kinase fusion cervical sarcoma, International Federation of Gynecology and Obstetrics Stage IB, in uterine cervix. |\n| uog70103-sup-0005-FigureS4.pptxPowerPoint 2007 presentation , 6.9 MB |\nFigure S4 Ultrasound (a–c), macroscopic (d) and microscopic (e) images of Case 5, diagnosed as high-grade endometrial stromal sarcoma, International Federation of Gynecology and Obstetrics Stage IB, in uterine cervix. |\n| uog70103-sup-0006-FigureS5.pptxPowerPoint 2007 presentation , 3.5 MB |\nFigure S5 Grayscale (a) and color Doppler (b) transvaginal ultrasound images showing relapse of neurotrophic tyrosine receptor kinase fusion cervical sarcoma (Case 4). |\n| uog70103-sup-0007-VideoS1.mp4MPEG-4 video, 70 MB |\nVideoclip S1 Grayscale and color Doppler ultrasound of leiomyosarcoma in uterine cervix, International Federation of Gynecology and Obstetrics Stage IB, in 37-year-old patient (Case 3). |\n| uog70103-sup-0008-VideoS2.mp4MPEG-4 video, 69.8 MB |\nVideoclip S2 Grayscale and color Doppler ultrasound of pleomorphic high-grade rhabdomyosarcoma in uterine cervix, International Federation of Gynecology and Obstetrics (FIGO) Stage IB, in 64-year-old patient (Case 1). In the corpus of the same uterus there was endometrial endometrioid adenocarcinoma, FIGO stage IA (synchronous tumors). |\n| uog70103-sup-0009-VideoS3.mp4MPEG-4 video, 86.7 MB |\nVideoclip S3 Grayscale and color Doppler ultrasound of leiomyosarcoma in uterine cervix, International Federation of Gynecology and Obstetrics Stage IB, in 35-year-old patient (Case 2). |\n| uog70103-sup-0010-VideoS4.mp4MPEG-4 video, 46.4 MB |\nVideoclip S4 Grayscale and color Doppler ultrasound of neurotrophic tyrosine receptor kinase fusion cervical sarcoma, International Federation of Gynecology and Obstetrics Stage IB, in 44-year-old patient (Case 4). |\n| uog70103-sup-0011-VideoS5.mp4MPEG-4 video, 29.2 MB |\nVideoclip S5 Grayscale and color Doppler ultrasound of high-grade endometrial stromal sarcoma, International Federation of Gynecology and Obstetrics Stage IB, in 29-year-old patient (Case 5). |\n| uog70103-sup-0012-VideoS6.mp4MPEG-4 video, 24 MB |\nVideoclip S6 Grayscale and color Doppler ultrasound showing relapse of neurotrophic tyrosine receptor kinase fusion cervical sarcoma (Case 4). |\n| uog70103-sup-0013-VideoS7.mp4MPEG-4 video, 19.8 MB |\nVideoclip S7 Ultrasound showing complete response to treatment with neurotrophic tyrosine receptor kinase (NTRK) inhibitors of relapse of NTRK fusion cervical sarcoma (Case 4). |\nPlease note: The publisher is not responsible for the content or functionality of any supporting information supplied by the authors. Any queries (other than missing content) should be directed to the corresponding author for the article.\nReferences\n- 1Fadare O. Uncommon sarcomas of the uterine cervix: a review of selected entities. Diagn Pathol. 2006; 1: 30-36.\n- 2Wright JD, Rosenblum K, Huettner PC, et al. Cervical sarcomas: an analysis of incidence and outcome. Gynecol Oncol. 2005; 99(2): 348-351.\n- 3Fadare O, Ghofrani N, Stamatakos MD, Tavassoli FA. Mesenchymal lesions of the uterine cervix. Pathology Case Reviews. 2006; 11(3): 140-152.\n10.1097/01.pcr.0000217868.84282.77Google Scholar\n- 4Bansal S, Lewin SN, Burke WM, et al. Sarcoma of the cervix: natural history and outcomes. Gynecol Oncol. 2010; 118(2): 134-138.\n- 5Ray-Coquard I, Casali PG, Croce S, et al. ESGO/EURACAN/GCIG guidelines for management of patients with uterine sarcomas. Int J Gynecol Cancer. 2024; 34(10): 1499-1521.\nArticle Metrics\nTotal unique accesses to an article’s full text in HTML or PDF/ePDF format.More metric information\nScite metrics\nExplore this article's citation statements on scite.ai\nShare QR Code\nGenerating QR code\nQR code copied to clipboard!\nSomething went wrong while generating your QR code. Please try again in a moment. If the issue persists, refresh the page or contact support.\nExport citation\nUnable to load citation data. Please try again in a moment.\nHow to cite\nElkins, L. J., & Spiegelman, M. (2021). pyUserCalc: A revised Jupyter notebook calculator for uranium-series disequilibria in basalts. Earth and Space Science, 8, e2020EA001619. https://doi.org/10.1029/2020EA001619\nDownload Citation\nIf you have the appropriate software installed, you can download article citation data to the citation manager of your choice. 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