{"paper_id":"9d75d7b0-ed52-475f-a028-07c02bbe6b82","body_text":"- Therapeutic vectors of treatment of ovarian endometriomas\nTherapeutic vectors of treatment of ovarian endometriomas\nHEALTH OF WOMAN. 2018.4(130):83–86; doi 10.15574/HW.2018.130.83\nShapoval O. S.\nSI «Zaporizhzhya Medical Academy of Postgraduate Education Ministry of Health of Ukraine»\nThe objective: to study clinical and anamnesis features in patients with ovarian endometriomas and to improve existing algorithms of treatment women with ovarian endpmetriomas.\nMaterials and methods. The study included 32 patients aged 18 – 49 years with ovarian endometriomas and 50 healthy women. A general clinical, sonographic, immunological examination was conducted.\nResults. The analysis of the study data revealed the I degree of insufficiency of the adaptive link and the I–II degree of insufficiency of the nonspecific link of the immune system. In 74.51% of cases surgical treatment of the pathological process was carried out. As a conservative therapy and in the postoperative period the patients received complex therapy with immunomodulators, drugs of indole-3-carbinol, combined oral contraceptives with gestagen.\nConclusion. The application of our proposed complex therapy of ovarian endometriomas in women of reproductive age showed a high recovery rate and a low relapse rate.\nKey words: ovarian endometrioma, reproductive age, immune dysfunction, treatment.\nREFERENCES\n1. Adamovskaya TN. 2013. Osobennosti vedeniya patsientok s endometrioz-assotsiirovannyim besplodiem. Zdorove zhenschiny 3(79):187–191.\n2. Asien P, Velasko I. 2014. Endometrioz: khvoroba, yaka zalyshaietsia zahadkoiu. Zdorovia Ukrainy 1:52–55.\n3. Gasparyan SA, Ionova RM, Popova OS. 2015. Endometrioz i fertilnost. Klyuchevyie momentyi lecheniya. Akusherstvo, ginekologiya, reproduktsiya 4:66–72.\n4. Guseynova OM. 2011. Osobennosti immunnogo otveta u zhenschin s genitalnyim endometriozom. Sarat. n.-med. zh. 4:804–808.\n5. Unanyan AL. 2010. Endometrioz i reproduktivnoe zdorove zhenschin. Akusherstvo, ginekologiya, reproduktsiya 3(4):6–11.\n6. Burney RO. 2013. The genetics and biochemistry of endometriosis. Curr. Opin. Obstet. Gynecol. 25:280–286. https://doi.org/10.1097/GCO.0b013e3283630d56; PMid:23759832\n7. Harada T. 2014. Endometriosis: Pathogenesis and Treatment. Japan. Springer.: 475. PMid:25193821\n8. Szamatowicz M. 2007. Endometriosis – is the best way of infertility treatment? IFFS. – Abstract Book. – FC 1505: 80.","source_license":"CC0","license_restricted":false}