{"paper_id":"8fe41631-3b16-4e7d-9940-2f9b98c40dd3","body_text":"ECR 2014 / C-1959\nPossibility of color doppler in predicting of steroid therapy efficiency in patients with adenomyosis\nThis poster is published under an open license. Please read the disclaimer for further details.\nCongress:\nECR 2014\nPoster Number:\nC-1959\nType:\nScientific Exhibit\nKeywords:\nOutcomes, Efficacy studies, Ultrasound-Colour Doppler, Ultrasound, Genital / Reproductive system female\nAuthors:\nK. Lobanov, A. Pomortsev, T. Makukhina, V. Vidyaeva; Krasnodar/RU\nDOI:\n10.1594/ecr2014/C-1959\nAims and objectives\nTo investigate bloodflow changes in myometrium during steroid therapy of adenomyosis.\nMethods and materials\n80 patients with adenomyosis diagnosed according to clinical symptoms,\ntransvaginal sonography with color Doppler ultrasound imaging (CD) and loop biopsy of myometrium were treated with standard steroid therapy (30 mkg of ethinylestradiol and 2 mg of dienogest) for 12 months.\nThe number of bloodflow loci was evaluated in the standard saggital uterus section with minimal sensitivity setting of Doppler system.\nThe saggital section area was calculated by manual operation excluding endometrium area.\nAfter that the average number of bloodflow loci per 1 square sm was...\nResults\nBefore steroid therapy a significant increase ofbloodflow loci number (LN) according to CD was observed in the patients with adenomyosis (р<0,01).\nThe LN in the first group decreased in 3 months (р<0,01) and no significant difference of vascularisation with the control group was found.\nFurther LN in this group didn’t change during observation.\nIn the second group recurrence of bleeding and/or dysmenorrhea served as indications for surgical treatment from 8 to 15 months since the beginning of treatment.\nIn this group there was no LN...\nConclusion\nPersistent high vascularisation level of miometrium according to CD may be used as a predictor of failed steroid therapy for patients with adenomyosis.\nPersonal information\nPomortsev Alexey Victorovich - professor,\nHead of Radiology Department of Kuban State Medical University.\nKrasnodar,[email protected]\nReferences\nSchindl M.,\nBirner P.,\nObermair A.,\nKiesel L.,\nWenzl R.\nIncreased microvessel density in adenomyosis uteri // Fertil.\nsteril.\n– 2001.\n– V.\n75.\n№ 1.\n– Р.\n131–135.\nMakukhina T.B.,\nPomortsev A.V.,\nLobanov K.A.\nDoppler sonography peculiarities of uterus tissual blood flow of patients with adenomyosis treated with steroid hormonal therapy.\nUltrasound in obstetrics and gynecology.\n– Oct. 2011,\nVol.\n38,\nsuppl.\n1.\n– P.\n265.\nMabrouk M.,\nFrasca C.,\nGeraci E.,\nMontanari G.,\nFerrini G.,\nRaimondo D.,\nAlvisi S.,\nParadisi R.,\nVilla G.,...","source_license":"CC0","license_restricted":false}