{"paper_id":"8ed1b65a-d948-48be-9002-25a84ca0ae18","body_text":"Abstract\nBackground\nEndometriosis affects the quality of life in women during their reproductive years, causing immense pain and can result in infertility. It is characterized by inflammation and the growth of the endometrium outside the uterine cavity. Metabolomics has the potential to resolve the major bottleneck of endometriosis which is delay in diagnosis due to the invasive diagnostic approach.In this review, the author has summarized the identified biomarkers of endometriosis from different bodily fluids. Metabolomics promises a non-invasive diagnostic approach for endometriosis that could aid in earlier diagnosis and prognosis.\nMethods\nPatients with endometriosis keywords were searched in correspondence with the assigned keywords, including metabolomics from PubMed, from its inception to Dec 2023. The relevant studies from this search were extracted and included in the study.\nResults\nThis article provides information regarding metabolomics studies in endometrisis.\nConclusions\nWe demonstrated that metabolomics is about to change the world of endometriosis by analyzing and detecting the diagnosis, prognosis, mortality and treatment response biomarkers.\nSimilar content being viewed by others\nData availability\nNot applicable\nCode availability\nNot applicable\nReferences\nGiudice LC, Kao LC (2004) Endometriosis. Lancet. 364(9447):1789–1799\nAngioni S (2017) New insights on endometriosis. Minerva Ginecol 69(5):438–439\nMehedintu C, Plotogea MN, Ionescu S, Antonovici M (2014) Endometriosis still a challenge. J Med Life 7(3):349–357\nCentini G, Ginetti A, Colombi I, Cannoni A, Giorgi M, Ferreira H et al (2024) Endometriosis of the appendix: prevalence, associated lesions, and proposal of pathogenetic hypotheses. A retrospective cohort study with prospectively collected data. 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Arch Gynecol Obstet 299(5):1501–1508\nFunding\nNot applicable.\nAuthor information\nAuthors and Affiliations\nContributions\nConception, design, analysis and interpretation of data, drafting the article, and final approval of the version to be published by Swarnima Pandey.\nCorresponding author\nEthics declarations\nConflict of interest\nAuthors have no conflicts of interest to declare.\nEthics approval\nNot applicable\nConsent to participate\nNot applicable\nConsent for publication\nYes\nAdditional information\nPublisher's Note\nSpringer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.\nRights and permissions\nSpringer Nature or its licensor (e.g. a society or other partner) holds exclusive rights to this article under a publishing agreement with the author(s) or other rightsholder(s); author self-archiving of the accepted manuscript version of this article is solely governed by the terms of such publishing agreement and applicable law.\nAbout this article\nCite this article\nPandey, S. Metabolomics for the identification of biomarkers in endometriosis. Arch Gynecol Obstet 310, 2823–2827 (2024). https://doi.org/10.1007/s00404-024-07796-5\nReceived:\nAccepted:\nPublished:\nVersion of record:\nIssue date:\nDOI: https://doi.org/10.1007/s00404-024-07796-5","source_license":"CC0","license_restricted":false}