{"paper_id":"86e7c0c8-15f8-438b-be94-eaba42914fa1","body_text":"Role of LHRH analogue in cases of refractory mastalgia\nKeywords:\nMastalgia, Complete estrogen blockade. GNRH analogue.Abstract\nBackground: Mastalgia is the commonest cause of visit to the breast clinic. The present study was conducted to assess the efficacy of complete estrogen\nblockade (CEB) with centchroman and LHRH analog goserelin in the treatment of refractory mastalgia. Aim: To study the effect of LHRH\nanalogue in refractory mastalgia and to increase pain free period in patients with refractory mastalgia. Methods: This is a prospective cohort\nstudy conducted in the Dept.Of Gen.Surgery IGIMS ,Patna over a period of six months.The reduction of pain score ( as measured by a visual\nanalog scale (VAS) recorded on a breast pain chart ) to 3 or less at 6 weeks of initiation of treatment was taken as primary objective. Results:\nFifty patients were enrolled in the study. The mean age of the patients was 28 years (15–45 years). The median duration of symptoms was 6 months\n(4–8). All of them had bilateral mastalgia. The mean pain score at start of study was 7. Conclusion: Complete estrogen blockade by means of GNRH\nanalogue is safe and effective for treatment of refractory mastalgia.\nDownloads\nPublished\nHow to Cite\nIssue\nSection\nLicense\nCopyright (c) 2022 Rinku Kumari, Ankur Akela, Pradeep Jaiswal, Pawan Kr. Jha\nThis work is licensed under a Creative Commons Attribution 4.0 International License.","source_license":"CC0","license_restricted":false}