{"paper_id":"868aaf90-80ee-48ba-9868-bf2bdee1f676","body_text":"Print ISSN: 1021-335X\nOnline ISSN: 1791-2431\nInternational Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.\nInternational Journal of Oncology is an international journal devoted to oncology research and cancer treatment.\nCovers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.\nOncology Reports is an international journal devoted to fundamental and applied research in Oncology.\nExperimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.\nOncology Letters is an international journal devoted to Experimental and Clinical Oncology.\nExplores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.\nInternational journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.\nMultidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.\nOpen-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.\nPublishes open-access research on using epigenetics to advance understanding and treatment of human disease.\nAn International Open Access Journal Devoted to General Medicine.\nReview\n- Authors:\n-\nPages: 1347-1356|Published online on: September 12, 2011https://doi.org/10.3892/or.2011.1456\n- Expand metrics +\nThis review summarizes data from recent molecular genetic and epidemiology studies of the generic term ‘female pelvic cancer’. The English-language literature was reviewed for genetic, epigenetic, epidemiologic and environmental risk factors. There are well-documented disparities among racial and ethnic groups with respect to epithelial ovarian cancer (EOC) prevalence. In the case of the serous histological subtype, primary EOC, fallopian tube cancer and peritoneal cancer could be regarded as a single disease entity. However, EOC is not a single disease. Comparing the profile of EOC between Japanese and Caucasians, clear cell carcinomas (27.6%) are more common in Japan, possibly with fewer serous adenocarcinomas (40.7%). This may reflect a proportional increase. The Japanese may exhibit a higher proportion of malignant transformation of endometriosis compared to the United States population. Although some part of the molecular genetic pathogenesis has been unveiled, the complete events of molecular genetic epidemiological changes associated with EOC remain to be identified. This review focuses on current knowledge of the genetic and environmental factors affecting the development of EOC, and outlines future challenges in its pathogenesis research.\nCopy and paste a formatted citation\nSpandidos Publications style\nHaruta S, Furukawa N, Yoshizawa Y, Tsunemi T, Nagai A, Kawaguchi R, Tanase Y, Yoshida S and Kobayashi H: Molecular genetics and epidemiology of epithelial ovarian cancer (Review). Oncol Rep 26: 1347-1356, 2011.\nAPA\nHaruta, S., Furukawa, N., Yoshizawa, Y., Tsunemi, T., Nagai, A., Kawaguchi, R. ... Kobayashi, H. (2011). Molecular genetics and epidemiology of epithelial ovarian cancer (Review). Oncology Reports, 26, 1347-1356. https://doi.org/10.3892/or.2011.1456\nMLA\nHaruta, S., Furukawa, N., Yoshizawa, Y., Tsunemi, T., Nagai, A., Kawaguchi, R., Tanase, Y., Yoshida, S., Kobayashi, H.\"Molecular genetics and epidemiology of epithelial ovarian cancer (Review)\". Oncology Reports 26.6 (2011): 1347-1356.\nChicago\nHaruta, S., Furukawa, N., Yoshizawa, Y., Tsunemi, T., Nagai, A., Kawaguchi, R., Tanase, Y., Yoshida, S., Kobayashi, H.\"Molecular genetics and epidemiology of epithelial ovarian cancer (Review)\". Oncology Reports 26, no. 6 (2011): 1347-1356. https://doi.org/10.3892/or.2011.1456","source_license":"CC0","license_restricted":false}