{"paper_id":"856fe846-5d56-466a-a792-87aa86636af9","body_text":"Print ISSN: 1021-335X\nOnline ISSN: 1791-2431\nInternational Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.\nInternational Journal of Oncology is an international journal devoted to oncology research and cancer treatment.\nCovers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.\nOncology Reports is an international journal devoted to fundamental and applied research in Oncology.\nExperimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.\nOncology Letters is an international journal devoted to Experimental and Clinical Oncology.\nExplores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.\nInternational journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.\nMultidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.\nOpen-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.\nPublishes open-access research on using epigenetics to advance understanding and treatment of human disease.\nAn International Open Access Journal Devoted to General Medicine.\nArticle\n- Authors:\n-\nPages: 49-101|Published online on: January 1, 1998https://doi.org/10.3892/or.5.1.49\n- Expand metrics +\nWe studied the expression of oncogenes and tumor-suppressor genes in human endometriosis in a retrospective pilot study. Sixteen patients with histologically verified pelvic endometriosis at the university-based tertiary care referral center were studied. Immunohistochemical determination of c-myc, c-erb-B2, nm23 and p53 expression in archival, paraffin-embedded pathological samples were used from patients operated upon for pelvic endometriosis. c-myc was expressed in 8/15 cases (53.3%). nm23 was expressed in 7/16 cases (43.7%). c-erb-B2 and p53 reactivity was undetectable in the samples studied. The c-myc oncogene and nm23 are overexpressed in many cases of endometriosis, and may play a still undefined role in its pathogenesis. Immuno-histochemistry is a useful tool for the study of oncogenic activation in this disease.\nCopy and paste a formatted citation\nSpandidos Publications style\nSchneider J, Jimenez E, Rodriguez F and del Tanago J: c-myc, c-erb-B2, nm23 and p53 expression in human endometriosis.. Oncol Rep 5: 49-101, 1998.\nAPA\nSchneider, J., Jimenez, E., Rodriguez, F., & del Tanago, J. (1998). c-myc, c-erb-B2, nm23 and p53 expression in human endometriosis.. Oncology Reports, 5, 49-101. https://doi.org/10.3892/or.5.1.49\nMLA\nSchneider, J., Jimenez, E., Rodriguez, F., del Tanago, J.\"c-myc, c-erb-B2, nm23 and p53 expression in human endometriosis.\". Oncology Reports 5.1 (1998): 49-101.\nChicago\nSchneider, J., Jimenez, E., Rodriguez, F., del Tanago, J.\"c-myc, c-erb-B2, nm23 and p53 expression in human endometriosis.\". Oncology Reports 5, no. 1 (1998): 49-101. https://doi.org/10.3892/or.5.1.49","source_license":"public-domain-us","license_restricted":false}