{"paper_id":"84f0f2f1-b77b-4ffb-a97d-253162019694","body_text":"Abstract\nEndometriosis is a chronic gynecologic disease with a pleiotropic symptomatology, physical presentation, and treatment approaches. Ten percent of the population is affected; however, the prevalence in chronic pelvic pain or infertility-stricken women is much higher. Surgical diagnosis is adequate, but the classification scheme is of little value to clinicians. Apart from a genetic component to endometriosis, there are other predisposing factors that are predominately estrogen driven. Several hypotheses exist, but there is no conclusive theory for either the pathophysiology of endometriosis or the mechanisms for attributed infertility and pain. This chapter describes approaches to treating infertility (both surgically and medically) as well as managing pain symptoms. As much as the literature provides, evidence-based studies have been summarized to maximize your treatment approaches to this vexing disease.\nAccess this chapter\nTax calculation will be finalised at checkout\nPurchases are for personal use only\nSimilar content being viewed by others\nAbbreviations\n- Chronic pelvic pain:\n-\nPain below the umbilicus that is of at least 6 months’ duration and causes functional disability\n- Deep endometriosis:\n-\nWhen the endometrial tissue invades deeper than 5 mm\n- Endometrioma:\n-\nOvarian cyst lined by endometrial tissue and containing thick, brown, tar-like fluid\n- Endometriosis:\n-\nEndometrial cells are found outside the uterus and lead to symptoms such as severe pelvic pain, dysmenorrhea, dyspareunia, and subfertility\n- Müllerianosis:\n-\nEndometrial tissue located at sites outside of the uterus during the embryologic period of organogenesis\n- Sampson’s theory:\n-\nRetrograde menstruum exits through the fallopian tubes into the pelvis and in some women this could eventually lead to the development and establishment of endometriosis\n- Subfertility:\n-\nReduced fertility over a prolonged period of time\nReferences\nSimoens S, Dunselman G, Dirksen C, Hummelshoj L, Bokor A, Brandes I, et al. 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Springer, Cham. https://doi.org/10.1007/978-3-319-52210-4_24\nDownload citation\nDOI: https://doi.org/10.1007/978-3-319-52210-4_24\nPublished:\nPublisher Name: Springer, Cham\nPrint ISBN: 978-3-319-52209-8\nOnline ISBN: 978-3-319-52210-4\neBook Packages: MedicineMedicine (R0)\nKeywords\n- Bone Mineral Density\n- Chronic Fatigue Syndrome\n- Interstitial Cystitis\n- Chronic Pelvic Pain\n- Combine Oral Contraceptive\nThese keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.","source_license":"CC0","license_restricted":false}