{"paper_id":"809e0013-a34e-4a99-9633-289c569a95bf","body_text":"Abstract\nPurpose\nAdenomyosis is a poorly understood entity with no unified treatment protocol. It has been thought to only affect the quality of life of older women, but growing evidence is highlighting the increased frequency of adenomyosis in younger patients and its possible effects on fertility outcomes. This can have a great impact on how clinicians screen, diagnose, and treat this condition. The aim of this review is to explore the relationship between adenomyosis and infertility.\nMethods\nA literature search of the keywords “adenomyosis”, “infertility”, “pregnancy” and “fertility” was conducted using the PubMed and Medline search engines. The articles selected were observational, systematic reviews, meta-analyses, and randomized controlled trials. The search was limited to English, abstracts were screened, and articles were selected.\nResults\nThe literature reports lower clinical pregnancy rates, lower live birth rates, higher miscarriage rates, and higher odds of adverse obstetric outcomes in patients with adenomyosis. Treatment seems to be associated with higher pregnancy rates and live births rates.\nConclusion\nAn association between adenomyosis and infertility seems to exist, and treatment could lead to improved fertility outcomes.\nAccess this article\nWe’re sorry, something doesn't seem to be working properly.\nPlease try refreshing the page. If that doesn't work, please contact support so we can address the problem.\nSimilar content being viewed by others\nReferences\nBird CC, McElin TW, Manalo-Estrella P. The elusive adenomyosis of the uterus–revisited. Am J Obstet Gynecol. 1972;112(5):583–93.\nGarcía-Solares J, et al. Pathogenesis of uterine adenomyosis: invagination or metaplasia? 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Obstet Gynecol Surv. 2016;71(9):557–68.\nAuthor information\nAuthors and Affiliations\nContributions\nAll authors contributed equally to this review paper.\nCorresponding author\nEthics declarations\nConflict of interest\nThe authors have no relevant financial or non-financial interests to disclose.\nAdditional information\nPublisher's note\nSpringer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.\nRights and permissions\nAbout this article\nCite this article\nMoawad, G., Kheil, M.H., Ayoubi, J.M. et al. Adenomyosis and infertility. J Assist Reprod Genet 39, 1027–1031 (2022). https://doi.org/10.1007/s10815-022-02476-2\nReceived:\nAccepted:\nPublished:\nVersion of record:\nIssue date:\nDOI: https://doi.org/10.1007/s10815-022-02476-2","source_license":"CC0","license_restricted":false}