{"paper_id":"7fcfb940-8a92-46fe-ae37-e03ebb25f34b","body_text":"Abstract\nObjective\nThe purpose of this study was to examine the recurrence rates of ovarian endometrioma, dysmenorrhea, dyspareunia, and related complications between sclerotherapy and laparoscopic ovarian cystectomy in individuals aged 25 to 38.\nMethods\nEighty-eight women participated in this retrospective, single-center study between January 2020 and February 2022. Patients received either laparoscopy or sclerotherapy, depending on the opinion of the pertinent physician. In this study, the following parameters were retrospectively analyzed in follow-up visits 2, 6 and 12 months after sclerotherapy and laparoscopy: dysmenorrhea and dyspareunia by visual analog scale, complications following the intervention, and serial pelvic sonograms for endometrioma cyst recurrence. Moreover, serum Anti-Müllerian hormone (AMH) level before and 6 months after sclerotherapy/surgery were analyzed. The collected data were then analyzed using R software.\nResults\nThe results demonstrate the efficiency of both sclerotherapy and laparoscopic techniques in reducing endometrioma-related dysmenorrhea and dyspareunia over a 12-month period. There was no statistically significant difference in the occurrence of complications and recurrence rate between these two therapies, and both are equally beneficial. Also, the rate of AMH decline after laparoscopy was higher than sclerotherapy; however there was not a statistically significant change in serum level of AMH in laparoscopy compared to the sclerotherapy after 6 months.\nConclusion\nConsidering all the data, it appears that sclerotherapy, with its lower cost, shorter hospital stay, and quicker return to activities, can be a laparoscopic alternative to endometrioma cyst removal. More studies are required.\nSimilar content being viewed by others\nReferences\nZondervan K, Becker C, Koga K, Missmer S, Taylor R, Vigano P. Endometriosis. 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Comparison of the therapeutic efficacy and ovarian reserve between catheter-directed sclerotherapy and surgical excision for ovarian endometrioma. Eur Radiol. 2021;31(1):543–8. https://doi.org/10.1007/s00330-020-07111-1.\nAcknowledgements\nWe are grateful to the staff at Shariati Hospital for their careful clinical work and accurate data gathering regarding the instances described in this study.\nFunding\nNo specific funding was obtained.\nAuthor information\nAuthors and Affiliations\nContributions\nAN developed the idea for the project. The study was designed by AN and AA, and MA, and SM collected data and performed the data analysis and takes full responsibility for the integrity of the data. MJ drafted the manuscript. The final version has been approved by all authors.\nCorresponding author\nEthics declarations\nConflict of interest\nThe authors declare that they have no conflicts of interest.\nConsent for Publication\nNot applicable.\nEthics Approval and Consent to Participate\nThe Ethics Committee of Tehran University of Medical Sciences approved this retrospective study, and the ethical approval code was IR.TUMS.MEDICINE.REC.1401.048. Informed consent was obtained from all individual participants included in the study.\nAdditional information\nPublisher's Note\nSpringer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.\nSamaneh Mohtashami, MD, Gynecologist; Masoome Jabarpour, Phd, Embryologist; Ashraf Aleyasin, MD, Gynecologist, Infertility Fellowship, Professor; Marzieh Aghahosseini, MD, Gynecologist, Infertility Fellowship, Professor; Ayda Najafian, MD, Gynecologist, Infertility Fellowship, Assistant Professor.\nRights and permissions\nSpringer Nature or its licensor (e.g. a society or other partner) holds exclusive rights to this article under a publishing agreement with the author(s) or other rightsholder(s); author self-archiving of the accepted manuscript version of this article is solely governed by the terms of such publishing agreement and applicable law.\nAbout this article\nCite this article\nMohtashami, S., Jabarpour, M., Aleyasin, A. et al. Efficacy of Ethanol Sclerotherapy Versus Laparoscopic Excision in the Treatment of Ovarian Endometrioma. J Obstet Gynecol India 74, 60–66 (2024). https://doi.org/10.1007/s13224-023-01840-1\nReceived:\nAccepted:\nPublished:\nVersion of record:\nIssue date:\nDOI: https://doi.org/10.1007/s13224-023-01840-1","source_license":"CC0","license_restricted":false}