{"paper_id":"7fa31426-4dd5-4b61-bec8-7397aec25221","body_text":"Abstract\nMatrix metalloproteinases belong to the key molecules of tissue remodeling involved in physiological and pathological processes of the female reproductive system. Adequate levels of their expression in the endometrium are essential for effective implantation and uneventful pregnancy. Chronic inflammatory process in the endometrium is associated with low tissue expression of metalloproteinase-9. Histologically verified chronic endometritis is associated with low serum activities of metalloproteinases 2 and 9, which are restored after combined etiotropic therapy. We measured serum levels of metalloproteinases in patients with chronic endometritis concomitant with sterility and its changes during the first days after magnetotherapy.\nSimilar content being viewed by others\nReferences\nA. V. Kuznetsova, V. C. Paukov, I. N. Voloshchuk, and E. M. Demidova, Arkh. Patol., No. 1, 18–22 (2002).\nV. I. Kulakov and A. V. Shurshalina, Ginekologiya, No. 11, 302–304 (2005).\nG. M. Soboleva, A. V. Shurshalina, and G. T. Sukhikh, Byull. Eksp. Biol. Med., 141, No. 2, 210–213 (2006).\nV. M. Strugatskii and E. S. Silantyeva, Akush. Ginekol., No. 6, 51–53 (2002).\nH. K. Choi, B. C. Choi, S. H. Lee, et al., Mol. Reprod. Dev., 66, 24–31 (2003).\nT. E. Curry and K. G. Osteen, Endocrinol. Rev., 24, 428–465 (2003).\nS. Goldman and E. Shalev, Front. Biosci., No. 9, 2474–2483 (2004).\nE. Hrabec, M. Strek, D. Nowak, and Z. Hrabec, Respir. Med., No. 1, 1–4 (2001).\nE. Hrabec, M. Strek, M. Zieba, et al., Int. J. Tuberc. Lung. Dis., No. 8, 713–719 (2002).\nD. L. Hulboy, L. A. Rudolf, and L. M. Matrisian, Mol. Hum. Reproduction, No. 3, 27–45 (1997).\nV. Lagente, B. Manoury, S. Nenan, et al., Braz. J. Med. Biol. Res., 10, 1521–1530 (2005).\nS. Lorenzl, D. S. Albers, N. Relkin, et al., Neurochem. Int., No. 3, 191–196 (2003).\nY. Niimi, R. Pawankar, and S. Kawana, Int. Arch. Allergy Immunol., No. 2, 104–113 (2006).\nJ. Renko, A. Kalela, and O. Jaakkola, Scand. J. Clin. Lab. Invest., No. 3, 255–261 (2004).\nI. Stamenkovic, J. Pathol., No. 4, 448–464 (2003).\nT. H. Vu and Z. Werb, Genes Dev., 17, 2123–2133 (2000).\nAuthor information\nAuthors and Affiliations\nCorresponding author\nAdditional information\n__________\nTranslated from Byulleten’ Eksperimental’noi Biologii i Meditsiny, Vol. 143, No. 4, pp. 455–457, April, 2007\nRights and permissions\nAbout this article\nCite this article\nSukhikh, G.T., Soboleva, G.M., Silantyeva, E.S. et al. Heterogeneity of serum activities of matrix metalloproteinases in chronic endometritis. Bull Exp Biol Med 143, 476–478 (2007). https://doi.org/10.1007/s10517-007-0160-5\nReceived:\nIssue date:\nDOI: https://doi.org/10.1007/s10517-007-0160-5","source_license":"CC0","license_restricted":false}