{"paper_id":"7edaba7b-8e58-4476-bea7-04fac315368b","body_text":"Print ISSN: 1107-3756\nOnline ISSN: 1791-244X\nInternational Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.\nInternational Journal of Oncology is an international journal devoted to oncology research and cancer treatment.\nCovers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.\nOncology Reports is an international journal devoted to fundamental and applied research in Oncology.\nExperimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.\nOncology Letters is an international journal devoted to Experimental and Clinical Oncology.\nExplores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.\nInternational journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.\nMultidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.\nOpen-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.\nPublishes open-access research on using epigenetics to advance understanding and treatment of human disease.\nAn International Open Access Journal Devoted to General Medicine.\nReview\n- Authors:\n-\nArticle Number: 32|Published online on: December 1, 2025https://doi.org/10.3892/ijmm.2025.5703\n- Expand metrics +\nEndometriosis is a complex, chronic inflammatory gynecological disorder with estrogen‑dependent characteristics that severely impairs the quality of life of women and potentially leads to infertility. However, its pathogenesis remains poorly understood. Exosomes, small, discoid vesicles released by nearly all cell types, serve essential functions in multiple biological processes, including immune evasion, cellular migration, and differentiation. These vesicles can transport a broad repertoire of bioactive molecules, cross cell membranes readily, and remain stable within cells and body fluids. The present review summarizes global research from the last two decades on the mechanistic associations between exosomes and endometriosis, emphasizing their potential as vehicles for therapeutic delivery. Notably, the biological hallmarks of endometriosis such as fibrosis, immune dysregulation, angiogenesis, and aberrant cellular proliferation and migration, align with exosomal functions, suggesting that exosomes may contribute to disease progression. Furthermore, the use of exosomes as natural carriers for endometriosis treatment has been proposed, suggesting novel therapeutic avenues.\nCopy and paste a formatted citation\nSpandidos Publications style\nChen W, Ma Y, Zhang X, Zhang S, Wu S, Lu Y and Tan J: Bridging bench to bedside: Exosome‑based strategies for endometriosis diagnosis and treatment (Review). Int J Mol Med 57: 32, 2026.\nAPA\nChen, W., Ma, Y., Zhang, X., Zhang, S., Wu, S., Lu, Y., & Tan, J. (2026). Bridging bench to bedside: Exosome‑based strategies for endometriosis diagnosis and treatment (Review). International Journal of Molecular Medicine, 57, 32. https://doi.org/10.3892/ijmm.2025.5703\nMLA\nChen, W., Ma, Y., Zhang, X., Zhang, S., Wu, S., Lu, Y., Tan, J.\"Bridging bench to bedside: Exosome‑based strategies for endometriosis diagnosis and treatment (Review)\". International Journal of Molecular Medicine 57.2 (2026): 32.\nChicago\nChen, W., Ma, Y., Zhang, X., Zhang, S., Wu, S., Lu, Y., Tan, J.\"Bridging bench to bedside: Exosome‑based strategies for endometriosis diagnosis and treatment (Review)\". International Journal of Molecular Medicine 57, no. 2 (2026): 32. https://doi.org/10.3892/ijmm.2025.5703","source_license":"CC0","license_restricted":false}