{"paper_id":"7cee2b1a-8798-4a37-bb39-ba1be196f454","body_text":"Abstract\nMethod\nWe performed direct intraperitoneal insemination in combination with superovulation and washed husband's spermatozoa as the treatment of infertility caused by oligospermia, cervical subfertility, or ovulatory dys-function or idiopathic infertility in 162 couples during 360 cycles.\nResults\nThe pregnancy rate per couple was 21.9% in the cervical-factor group, 20.9% in the idiopathic group, 4.9% in the oligospermia group, and 15.5% in the ovulatory dysfunction group.\nConclusion\nThe pregnancy rate was 33.3% for all couples and 15.0% for all cycles.\nSimilar content being viewed by others\nReferences\nLopata A, Patullo MJ, Chang A, James B: A method for collecting motile spermatozoa from human semen. Fertil Steril 1976;27:677–684\nManhes H, Hermahessiere J: Fécondation intra-péritonéale. Première grossesse obtenue sur indication masculine. Oral presentation, 3rd International Forum Andrology, Paris, June 1985\nForrler A, Dallenbach P, Nisand I, Moreau L, Cranz C, Clavert A, Rumpler Y: Direct intraperitoneal insemination in unexplained and cervical infertility. Lancet 1986;1:916–917\nSeracchioli R, Melega C, Maccolini A, Cattoli M, Bulletti C, Bovicelli L, Flamigni C: Pregnancy after direct intraperitoneal insemination. Hum Reprod 1991;6:533–536\nArici A, Byrd W, Bradshaw K, Kutteh WH, Marshburn P, Carr BR: Evaluation of clomiphene citrate and human chorionic gonadotropin treatment: A prospective, randomized, crossover study during intrauterine insemination cycles. Fertil Steril 1994;61:314–318\nBelaisch-Allart JC, Frydman R, Testart J, Guillet-Rosso F, Lassale B, Volante M, Papiernik E: In vitro fertilization and embryo transfer program in Clamart, France. J Vitro Fert Embryo Transf 1984;1:51–55\nTestart J, Amiel ML: Contribution of preovulatory-phase small follicles to the ovarian response in stimulated cycles. Hum Reprod 1991;6:823–827\nMenezo Y: Milieu synthétique pour la survie et la maturation des gamètes et pour la culture de l'∄uf fécondé. CR Acad Sci (D) (Paris) 1976;282:1967–1970\nWorld Health Organization (WHO): Laboratory Manual for the Examination of Human Semen and Semen-Cervical Mucus Interaction. Cambridge, Cambridge University Press, 1987\nFishel SB, Edwards RG, Purdy JM, Steptoe PC, Webster J, Walters E, Cohen J, Fehilly C, Hewitt J, Rowland G: Implantation aboration and birth after in vitro fertilization using the natural menstrual cycle or follicular stimulation with clomiphene citrate and human menopausal gonadotropin. J Vitro Fert Embryo Transfer 1985;2:123–131\nSerhal PF, Katz M, Little V, Woronowski H: Unexplained infertility—the value of Pergonal superovulation combined with intrauterine insemination. Fertil Steril 1988;49:602–606\nHorbay GLA, Cowell CA, Casper RF: Multiple follicular recruitment and intrauterine insemination outcomes compared by age and diagnosis. Hum Reprod 1991;6:947–952\nKarlström PO, Bakos O, Palmstierna M, Bergh T, Lundkvist ö: Direct intraperitoneal insemination-clinical results and comparisons between two methods of sperm preparation. Fertil Steril 1991;56:939–945\nDickey RP, Olar TT, Taylor DN, Curole DN, Rye PH: Sequential clomiphene citrate and human menopausal gonadotrophin for ovulation induction: Comparison to clomiphene citrate alone and human menopausal gonadotrophin alone. Hum Reprod 1993;8:56–59\nDodson WC, Whiteside DB, Huges CL, Easley H, Haney AF: Superovulation with intrauterine insemination in the treatment of infertility: A possible alternative to gamete of intrafallopian transfer andin vitro fertilization. Fertil Steril 1987;48:441–445\nDodson WC, Haney AF: Controlled ovarian hyperstimulation and intrauterine insemination for treatment of infertility. Fertil Steril 1991;55:457–467\nJenkins DM, O'Donavan P: Direct intraperitoneal insemination. Lancet 1988;1:655\nWittemer C, Menard A, Moreau L, Dellanbach P: The present perspectives of direct intraperitoneal insemination.In Advances in Assisted Reproductive Technologies, S Mashiach, Z Ben-Rafael, N Laufer, JG Schenker (eds). New York, Plenum Press, 1990, p 259\nCrosignani PG, Ragni G, Finzi GCL, De Lauretis L, Olivares MD, Perotti L: Intraperitoneal insemination in the treatment of male and unexplained infertility. Fertil Steril 1991;55:333–337\nCompos-Lietz E, Insull M, Kennedy SH, Ellis JD, Sargeant I, Barlow DH: A controlled assessment of direct intraperitoneal insemination. Fertil Steril 1992;57:168–173\nThurhan Nö, Artini PG, D'Ambrogio G, Droghini F, Volpe A, Genazzani AR: Studies on direct intraperitoneal insemination in the management of male factor, cervical factor, unexplained and immunological infertility. Hum Reprod 1992;7:66–77\nCimino C, Guestalla G, Comparetto G, Gullo D, Perino A, Beningno MA, Barba G, Cittadini E: Direct intraperitoneal insemination (DIPI) for the treatment of refractory infertility unrelated to female organic pelvic disease. Acta Eur Fertil 1988; 19:61–68\nAuthor information\nAuthors and Affiliations\nRights and permissions\nAbout this article\nCite this article\nRhouma, K.B., Miled, E.B., Marzouk, A.B. et al. Direct intraperitoneal insemination and controlled ovarian hyperstimulation in subfertile couples. J Assist Reprod Genet 11, 189–192 (1994). https://doi.org/10.1007/BF02211807\nReceived:\nAccepted:\nIssue date:\nDOI: https://doi.org/10.1007/BF02211807","source_license":"CC0","license_restricted":false}