{"paper_id":"7b1dfa25-de47-46af-9a6b-c8db412ee779","body_text":"Abstract\nAdenomyosis is due to the invasion or presence of endometrial glands in the uterine myometrium accompanied by hyperplasia and hypertrophy of the surrounding muscle cells, forming diffuse or focal lesions. Adenomyosis occurs most often in women between the ages of 30 and 50, but it can also be in younger women who have not had children. The incidence of adenomyosis is about 20–30% of reproductive-aged women, but this varies according to the particular population [1]. Recently, there appears to have a significant increase in the incidence and younger age patients. Thirty-five percent of patients are without symptoms, 15–30% associated with pelvic endometriosis, and 50% with uterine fibroids. The pathogenesis of adenomyosis is unknown, but in some patients, there is a belief that any intrauterine manipulations such as surgical termination of pregnancy can damage the endometrium’s basal layer, causing the endometrial gland to invade into the myometrium thus increasing the extent and severity of adenomyosis. Adenomyosis can then lead to dysmenorrhea and increased menstrual flow, infertility, and other related symptoms [2]. This disease seriously affects women’s physical and mental health.\nAccess this chapter\nTax calculation will be finalised at checkout\nPurchases are for personal use only\nSimilar content being viewed by others\nReferences\nNaftalin J, et al. How common is adenomyosis? A prospective study of prevalence using transvaginal ultrasound in a gynaecology clinic. Hum Reprod. 2012;27(12):3432–9.\nPeric H, Fraser I. The symptomatology of adenomyosis. Best Pract Res Clin Obstet Gynaecol. 2006;20(4):547–55.\nBernardi M, et al. Dysmenorrhea and related disorders. 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Fertil Steril. 2011;95(3):1152–5.\nAuthor information\nAuthors and Affiliations\nCorresponding author\nRights and permissions\nCopyright information\n© 2021 The Author(s), under exclusive license to Springer Nature Singapore Pte Ltd.\nAbout this chapter\nCite this chapter\nWong, F., Zhang, L., Wang, Z. (2021). Adenomyosis and HIFU Ablation. In: Focused Ultrasound Surgery in Gynecology. Springer, Singapore. https://doi.org/10.1007/978-981-16-0939-8_5\nDownload citation\nDOI: https://doi.org/10.1007/978-981-16-0939-8_5\nPublished:\nPublisher Name: Springer, Singapore\nPrint ISBN: 978-981-16-0938-1\nOnline ISBN: 978-981-16-0939-8\neBook Packages: MedicineMedicine (R0)","source_license":"CC0","license_restricted":false}