{"paper_id":"7a4a00e7-1cdc-4b24-bf29-2f57bf3f4f8e","body_text":"Abstract\nPrimary dysmenorrhoea may be regarded as a syndrome that includes not only pain in the lower abdomen and back but also a variety of other symptoms. However, pain is the primary complaint, often attributed to uterine cramps, which makes the uterus a focus of attention. Amongst the various factors that may be responsible for this pain, uterine hyper-contractility has received particular attention. When it became evident that prostaglandins play a major role in the control of uterine contractility it was logical to try and suppress the synthesis of these substances with prostaglandin synthetase inhibitors (PGSI) and thereby prevent uterine cramps.\nPreview\nUnable to display preview. Download preview PDF.\nSimilar content being viewed by others\nReferences\nAkerlund, M. (1978). Pathophysiology of dysmenorrhoea. Symposium on Prostaglandins and Dysmenorrhoea, Helsinki, 1978. Acta Obstet. Grnec. Scand. (Suppl.) 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J. Obstet. Grnecol. Br. C mrbh, 72, 185\nPulkkinen, M. O. and Kaihola, H.-L. (1977). Mefenamic acid in dysmenorrhoea. Acio Obstet. Grnecol Scand, 56. 75\nShangold. M. M., Aksel, S., Schoenberg, D. W. and Hammond, C. B. (1976). Plasma prostaglandin F2, levels in dysmenorrhoeic women. Feet. Steril, 27, 1171\nEditor information\nEditors and Affiliations\nRights and permissions\nCopyright information\n© 1979 MTP Press Limited\nAbout this chapter\nCite this chapter\nWiqvist, N. (1979). Prostaglandins and their Synthesis Inhibitors in Primary Dysmenorrhoea. In: Karim, S.M.M. (eds) Practical Applications of Prostaglandins and their Synthesis Inhibitors. Advances in Prostaglandin Research. Springer, Dordrecht. https://doi.org/10.1007/978-94-011-7843-3_11\nDownload citation\nDOI: https://doi.org/10.1007/978-94-011-7843-3_11\nPublisher Name: Springer, Dordrecht\nPrint ISBN: 978-94-011-7845-7\nOnline ISBN: 978-94-011-7843-3\neBook Packages: Springer Book Archive\nKeywords\nThese keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.","source_license":"CC0","license_restricted":false}