{"paper_id":"79ec9c5d-49c7-49d7-8831-058e5606f21b","body_text":"Abstract\nBackground\nTo evaluate the long-term symptoms, quality of life (QOL), and fertility after colorectal resection for endometriosis.\nMethods\nExtended analysis of a randomized controlled trial including 52 patients with colorectal endometriosis, comparing laparoscopically assisted to open colorectal resection. All included patients were invited to complete questionnaires evaluating the presence and intensity of symptoms and QOL using the SF-36 and fertility at a mean (SD) follow-up of 50.7 (13.8) months. We compared symptoms intensity and QOL before and after surgery at short- (mean follow-up of 19 months) and long-term (mean follow-up of 51 months).\nResults\nPersistent improvement in QOL was noted after surgery without differences between short and long term. Self-catheterization >6 months was the sole factor decreasing the long-term QOL (P = 0.02). No difference in symptoms and QOL was noted according to the route. Among the 28 patients (53.8 %) wishing to conceive, 12 (42.9 %) conceived within a mean (SD) time of 17 (13) months. No difference in fertility including pregnancy after IVF was noted between the routes, but spontaneous pregnancy occurred only after laparoscopy (P = 0.016).\nConclusions\nSymptoms and QOL improvements after colorectal resection last for over 4 years without difference between the routes. Thank to a lower intra- and postoperative complications and higher spontaneous pregnancy rate, laparoscopic colorectal resection should be the first surgical approach.\nSimilar content being viewed by others\nReferences\nWeed JC, Ray JE (1987) Endometriosis of the bowel. Obstet Gynecol 69:727–730\nMacafee CH, Greer HL (1960) Intestinal endometriosis. A report of 29 cases and a survey of the literature. 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Touboul, Ballester, Dubernard, Zilberman, Thomin and Daraï have no conflicts of interest or financial ties to disclose.\nAuthor information\nAuthors and Affiliations\nCorresponding authors\nAdditional information\nTrial registration number: NCT00939861.\nRights and permissions\nAbout this article\nCite this article\nTouboul, C., Ballester, M., Dubernard, G. et al. Long-term symptoms, quality of life, and fertility after colorectal resection for endometriosis: extended analysis of a randomized controlled trial comparing laparoscopically assisted to open surgery. Surg Endosc 29, 1879–1887 (2015). https://doi.org/10.1007/s00464-014-3880-4\nReceived:\nAccepted:\nPublished:\nIssue date:\nDOI: https://doi.org/10.1007/s00464-014-3880-4","source_license":"CC0","license_restricted":false}