{"paper_id":"797c07da-942b-4bf4-b25a-d6a0ae365f96","body_text":"Abstract\nHormone therapy remains an integral part of the treatment of hormone receptor-positive breast cancers. Tamoxifen, a selective estrogen receptor modulator, is the most common hormonal agent used in this scenario. Selective estrogen receptor modulators (SERMs) are competitive inhibitors of estrogen receptors which have an estrogen agonist and antagonist effect depending on target tissues. The antiestrogenic effect is by blocking the binding of estrogen to estrogen receptors.\nAccess this chapter\nTax calculation will be finalised at checkout\nPurchases are for personal use only\nSimilar content being viewed by others\nReferences\nDavies C, Pan H, Godwin J, Gray R, Arriagada R, Raina V, et al. Long-term effects of continuing adjuvant tamoxifen to 10 years versus stopping at 5 years after diagnosis of estrogen receptor-positive breast cancer: ATLAS, a randomized trial. Lancet 2013;381:805–16.\nFisher B, et al. 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The value of sonohysterography in the prediction of endometrial pathology in asymptomatic postmenopausal breast cancer tamoxifen treated patients. Gynecol Oncol. 2004;94:754–9.\nAuthor information\nAuthors and Affiliations\nCorresponding author\nEditor information\nEditors and Affiliations\nRights and permissions\nCopyright information\n© 2015 Springer India\nAbout this chapter\nCite this chapter\nSuchetha, S. (2015). Effects of Tamoxifen and Other SERMs in the Endometrium and Follow-Up of Patients. In: Rajaram, S., K, C., Maheshwari, A. (eds) Uterine Cancer. Springer, New Delhi. https://doi.org/10.1007/978-81-322-1892-0_41\nDownload citation\nDOI: https://doi.org/10.1007/978-81-322-1892-0_41\nPublisher Name: Springer, New Delhi\nPrint ISBN: 978-81-322-1891-3\nOnline ISBN: 978-81-322-1892-0\neBook Packages: MedicineMedicine (R0)\nKeywords\n- Endometrial Cancer\n- Breast Cancer Mortality\n- Selective Estrogen Receptor Modulator\n- Endometrial Thickness\n- Endometrial Hyperplasia\nThese keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.","source_license":"CC0","license_restricted":false}