{"paper_id":"71b264f0-362e-4ab8-a630-8f871a59936f","body_text":"ABSTRACT\nObjective\nIs to evaluate the efficacy of different ovarian stimulation (OS) protocols in patients with intact endometrioma(s) undergoing ICSI.\nMaterial and Methods\nRetrospective chart review was performed. A total of 717 women were detected to have endometriosis of which 165 women with intact endometrioma(s) were included in the final analysis. A total of 60 women were detected in long agonist (AG) and 105 in short antagonist protocol (ANT). Sub-group analysis was performed to document OS outcomes of poor responders fulfilling the Bologna criteria.\nResults\nSignificantly shorter cycle duration and lower gonadotropin consumption was observed with ANT protocol compared to AG (p<0.001). The OS outcomes in terms of implantation, ongoing pregnancy (OP) and live birth rate per started cycle (LBR) were comparable in both groups. Overall LBR was 22,4%. Both protocols revealed similar but poor reproductive outcomes in terms of ongoing pregnancy (11.1%) and live birth rates (7.4%) in poor responders.\nConclusion\nAG or ANT protocols seemed to be equally effective in terms of oocyte yield and LBRs in women with intact endometrioma undergoing OS. Shorter duration and lower gonadotropin consumption may be attributed to the convenience of ANT protocol. In poor responders, reproductive outcomes are still not satisfactory with either protocol","source_license":"CC0","license_restricted":false}