{"paper_id":"6e1d61ad-ec42-4cd6-83da-864dabb0c170","body_text":"Abstract\nThis is a disease principally of parous women in the later years of their reproductive life, and is characterized by the presence of endometrial tissue deep within the myometrium (Figure 17.1): there is almost invariably an associated hypertrophy of smooth muscle fibres around the islands of ectopic endometrium. When considering this condition it has always to be borne in mind that the interface between the normal endometrium and the myometrium is often very irregular, and that tangential cutting of the basal endometrium may produce apparently isolated islands of endometrial tissue surrounded by myometrium. It is for this reason that the word 'deep' is insisted upon in the definition of adenomyosis though there has been considerable dispute as to its interpretation. Very often it has been suggested that to justify a diagnosis of adenomyosis the ectopic endometrium should be one high power microscopic field, or a proportion of a low power microscopic field, below the base of the endometrium; but these are poorly defined criteria which take no account of variations in myometrial thickness, and the defining criterion that the intramyometrial glands must be at a distance of more than one quarter of the full thickness of the uterine wall below the endometrial—myometrial junction is to be preferred.\nPreview\nUnable to display preview. Download preview PDF.\nSimilar content being viewed by others\nReferences\nHendrickson, M. R. and Kempson, R. L. (1980). Surgical Pathology of the Uterine Corpus, (Philadelphia, London, Toronto: W. B. Saunders )\nLanglois, P. L. (1970). The size of the normal uterus. J. Reprod. Med., 4, 220–228\nTiltman, A. J. (1980). Adenomatoid tumours of the uterus. Histopathology, 4, 437–443\nQuigley, J. C. and Hart, W. R. (1981). Adenomatoid tumors of the uterus. Am. J. Clin. Pathol., 76, 627–635\nFerenczy, A., Fenoglio, J. and Richart, R. M. (1972). Observations on benign mesothelioma of the genital tract (adenomatoid tumor): a comparative ultrastructural study. Cancer, 30, 244 - 260\nSalazar, H., Kanbour, A. and Burgess, F. (1972). Ultrastructure and observations on the histiogenesis of mesotheliomata ‘adenomatoid tumors’ of the female genital tract. Cancer, 29, 141 - 152\nLangley, F. A. (1973). The pathology of the myometrium. In Fox, H. and Langley, F. A. (eds.). Postgraduate Obstetrical and Gynaecological Pathology. pp. 147 - 175. ( Oxford: Pergamon Press )\nSilverberg, S. G., Willson, M. A. and Board, J. A. (1971). Hemangiopericytoma of the uterus: an ultrastructural study. Am. J. Obstet. Gynecol., 110, 397–-404\nLangley, F. A. (1976). Malignant tumours of the uterine mesenchyme. Clin. Obstet. Gynaecol., 3, 425 - 457\nAuthor information\nAuthors and Affiliations\nRights and permissions\nCopyright information\n© 1983 H. Fox and C. H. Buckley\nAbout this chapter\nCite this chapter\nFox, H., Buckley, C.H. (1983). Myometrium: Non—Neoplastic Conditions and Miscellaneous Neoplasms. In: Atlas of Gynaecological Pathology. Current Histopathology, vol 5. Springer, Dordrecht. https://doi.org/10.1007/978-94-015-7312-2_17\nDownload citation\nDOI: https://doi.org/10.1007/978-94-015-7312-2_17\nPublisher Name: Springer, Dordrecht\nPrint ISBN: 978-94-015-7314-6\nOnline ISBN: 978-94-015-7312-2\neBook Packages: Springer Book Archive\nKeywords\n- Malignant Mesothelioma\n- Endometrial Tissue\n- Endometrial Stromal Sarcoma\n- Normal Endometrium\n- Smooth Muscle Fibre\nThese keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.","source_license":"CC0","license_restricted":false}