{"paper_id":"6b87f8da-ea28-4c16-89ca-810e6aad49d2","body_text":"Abstract\nClear cell carcinoma (CCC) of the ovary has clinical and pathological features distinct from those of other ovarian carcinomas. Most reports of CCC in the literature consist of relatively small numbers of cases. Recently, an international clinical trial for CCC was conducted by the Japan Gynecologic Oncology Group (JGOG) and 652 cases were collected and underwent central pathological review. This Atlas represents the results of that review, and comprises both typical and unusual pathological features.\nAccess this chapter\nTax calculation will be finalised at checkout\nPurchases are for personal use only\nSimilar content being viewed by others\nReferences\nInternational Agency for Research on Cancer. http://globocan.iarc.fr\nJemal A, Siegel R, Ward E et al (2007) Cancer statistics. Cancer J Clin 57:43–66\nConte PF, Cianci C, Gadducci A (1999) Update in the management of advanced ovarian carcinoma. Crit Rev Oncol Hematol 32:49–58\nBast RC Jr, Hennessy B, Mills GB (2009) The biology of ovarian cancer: new opportunities for translation. Nat Rev Cancer 9:415–428\nWinter WE 3rd, Maxwell GL, Tian C et al (2007) Prognostic factors for stage III epithelial ovarian cancer: a Gynecologic Oncology Group Study. J Clin Oncol 25:3621–3627\nOzols RF (2002) Future directions in the treatment of ovarian cancer. Semin Oncol 29:32–42\nMcGuire V, Jesser CA, Whittemore AS (2002) Survival among U.S. women with invasive epithelial ovarian cancer. Gynecol Oncol 84:399–403\nGilks CB, Ionescu DN, Kalloger SE et al (2008) Ovarian Cancer Outcomes Unit of the British Columbia Cancer Agency. Tumor cell type can be reproducibly diagnosed and is of independent prognostic significance in patients with maximally debulked ovarian carcinoma. Hum Pathol 39:1239–1251\nSugiyama T, Kamura T, Kigawa J et al (2000) Clinical characteristics of clear cell carcinoma of the ovary: a distinct histologic type with poor prognosis and resistance to platinum-based chemotherapy. Cancer 88:2584–2589\nTakano M, Kikuchi Y, Yaegashi N et al (2006) Clear cell carcinoma of the ovary: a retrospective multicentre experience of 254 patients with complete surgical staging. Br J Cancer 94:1369–1374\nItamochi H, Kigawa J, Sugiyama T et al (2002) Low proliferation activity may be associated with chemoresistance in clear cell carcinoma of the ovary. Obstet Gynecol 100:281–287\nItamochi H, Kigawa J, Terakawa N (2008) Mechanisms of chemoresistance and poor prognosis in ovarian clear cell carcinoma. Cancer Sci 99:653–658\nReed N (2010) Rare and uncommon gynecological cancers, a clinical guide. Springer, Berlin Heidelberg. ISBN:3642134912\nKennedy AW, Biscotti CV, Hart WR et al (1989) Ovarian clear cell adenocarcinoma. Gynecol Oncol 32:342–349\nCrozier MA, Copeland LJ, Silva EG et al (1989) Clear cell carcinoma of the ovary: a study of 59 cases. Gynecol Oncol 35:199–203\nJapan Society of Obstetrics and Gynecology (2013) Annual report. Acta Obstetrics et Gynecology Japonica 65:1032\nJacoby VL, Fujimoto VY, Giudice LC et al (2010) Racial and ethnic disparities in benign gynecologic conditions and associated surgeries. Am J Obstet Gynecol 202:514–521\nOlsen CM, Nagle CM, Whiteman DC et al (2008) Australian Cancer Study (Ovarian Cancer) and Australian Ovarian Cancer Study Group body size and risk of epithelial ovarian and related cancers: a population-based case-control study. Int J Cancer 123:450–456\nPfeiffer RM, Park Y, Kreimer AR et al (2013) Risk prediction for breast, endometrial, and ovarian cancer in white women aged 50 years or older: derivation and validation from population-based cohort studies. PLoS Med 10:e1001492\nBulun SE (2009) Endometriosis. N Engl J Med 360:268–279\nPearce CL, Templeman C, Rossing MA, Consortium OCA et al (2012) Association between endometriosis and risk of histological subtypes of ovarian cancer: a pooled analysis of case-control studies. Lancet Oncol 13:385–394\nMink PJ, Sherman ME, Devesa SS (2002) Incidence patterns of invasive and borderline ovarian tumors among white women and black women in the United States. Results from the SEER Program, 1978–1998. Cancer 95:2380–2389\nScarfone G, Bergamini A, Noli S et al (2014) Characteristics of clear cell ovarian cancer arising from endometriosis: a two center cohort study. Gynecol Oncol 133:480–484\nAuthor information\nAuthors and Affiliations\nRights and permissions\nCopyright information\n© 2015 Springer Japan\nAbout this chapter\nCite this chapter\nKigawa, J., Kaku, T., Sugiyama, T., Silverberg, S.G. (2015). Introduction. In: Atlas of Clear Cell Carcinoma of the Ovary. Springer, Tokyo. https://doi.org/10.1007/978-4-431-55438-7_1\nDownload citation\nDOI: https://doi.org/10.1007/978-4-431-55438-7_1\nPublisher Name: Springer, Tokyo\nPrint ISBN: 978-4-431-55437-0\nOnline ISBN: 978-4-431-55438-7\neBook Packages: MedicineMedicine (R0)\nKeywords\n- Ovarian Cancer\n- Epithelial Ovarian Cancer\n- Histological Subtype\n- Clear Cell Carcinoma\n- Increase Body Mass Index\nThese keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.","source_license":"CC0","license_restricted":false}