{"paper_id":"62983bfa-508a-4723-a5c5-dcc5e1f9b70b","body_text":"Subscribe to RSS\nDOI: 10.1055/s-0035-1558372\nInterobserver agreement of non-invasive diagnosis of endometriosis by transvaginal sonography (TVS)\nObjectives:\nEvaluation of the interobserver agreement and accuracy of transvaginal sonography (TVS) for deep infiltrating endometriosis (DIE) and endometriomas.\nMethods:\nSixty-seven consecutive patients were enrolled from January 2013 to January 2014 referred to a pelvic pain clinic and scheduled for laparoscopy and were prospectively examined by two experienced sonographers (observer A and B) independently and blinded to the others results. Gwet's first order agreement coefficient (Gwet's AC1) was used to calculate interobserver agreement and diagnostic accuracy of TVS as well as sensitivity, specificity, positive and negative predictive value (PPV, NPV) of TVS (observer A and B) when compared to laparoscopy.\nResults:\nSixty-five out of 67 patients were finally analysed. The level of agreement between observer A and B (Gwet's AC1), sensitivity/specificity were as following: vagina (Gwet's AC1: 0.933; 62%/94%; 82%/94%), bladder (Gwet's AC1: 1.00; 67%/97%; 67%/97%), uterosacral ligaments (USL) (Gwet's AC1: 0.84; 73%/83%; 53%/93%), adnexia (Gwet's AC1: 0.95; 71%/93%; 71%/93%), rectovaginal septum (RVS) (Gwet's AC1: 0.95; 40%/90%; 33%/87%) and rectosigmoid (Gwet's AC1: 0.98; 93%/96%; 94%/98%) reflecting high interobserver agreement. With the exception of DIE affecting the RVS, similar results were observed when TVS was compared with laparoscopy.\nConclusions:\nTVS is a highly accurate and reproducible method for non-invasive diagnosis of DIE in well-trained staff.","source_license":"CC0","license_restricted":false}