{"paper_id":"6243ba78-8f06-4a06-a555-6b4c8fc5d732","body_text":"Summary\nIn order to study the angiogenesis in endometriosis, the samples of eutopic and ectopic endometria from patients with endometriosis were quantitatively analyzed by color morphometric image system (CMIS) for vascular surface area, and by examining endometrial blood vessel for microvessel density (MVD). The results showed that within each menstrual phase the vascular surface area and MVD were significantly higher in ectopic endometria with endometriosis than those in eutopic endometria with endometriosis or normal endometrium (P<0.05). It is concluded that angiogenesis might be involved in the development of endometriosis.\nSimilar content being viewed by others\nReferences\nPotgen A J, Lubsen M C, Schoenmakers D Jet al., Vascular permeability factor expression influences tumor angiogenesis in human meanoma lines xenografted to nude mice. Am J Pathol, 1993, 146:147\nKoch A E, Harlow G, Haines E,et al. Vascular endothelial growth factor. A cytokine modulating endothelial function in rheumatoid arthritis. J Immunol, 1995, 152: 4149\nRavindranath N L, Little-Ihring H S, Phillips Net al. Vascular endothelial growth factor messenger ribonucleic acid expression in the primate ovary. Endocrinology, 1992, 131:254\nBreier G, Albrecht U, Sterrer S,et al. Expression of vascular endothelial growth factor during embryonic angiogenesis and endothelial cell differentiation. Development (Camb.), 1992, 114;521\nSmith S K. Angiogenesis. Semin Reprod Endocrinol, 1996, 15:221\nNisolle M F, Cassanas-Roux V, Anaf J Met al. Morphometric study of the stromal vascularition in peritoneal endometriosis. Fertil Steril, 1993, 59:442\nAuthor information\nAuthors and Affiliations\nAdditional information\nLIU Yi, male, born in 1968, Associate Professor\nRights and permissions\nAbout this article\nCite this article\nYi, L., Liqun, L. & Guijin, Z. Anginogenesis of eutopic and ectopic endometria in endometriosis. Current Medical Science 23, 190–191 (2003). https://doi.org/10.1007/BF02859954\nReceived:\nPublished:\nIssue date:\nDOI: https://doi.org/10.1007/BF02859954","source_license":"CC0","license_restricted":false}