{"paper_id":"618d0b6d-7cff-488f-b1cf-38a4b7f2b28b","body_text":"The importance of compression sonoelastography in improving the diagnostics of the pathology of myometrium\nDOI:\nhttps://doi.org/10.21303/2504-5679.2021.001908Keywords:\nadenomyosis, leiomyoma, compression sonoelastography, uterus, myometrium, ultrasound, study, image, deformation ratio, densityAbstract\nThe diversity of the clinical picture and the asymptomatic nature of the clinical manifestations of myometrial pathology cause difficulties in diagnosis. There is a lack of reliable diagnostic criteria for this pathology, in particular, imaging, especially with the simultaneous combination of adenomyosis and leiomyoma.\nThe aim of the research. Determination of the possibility of compression sonoelastography in the diagnosis of myometrial pathology and determination of its sonoelastography characteristics in leiomyoma and adenomyosis, as well as comparison of sonoelastography results with histological data.\nMaterials and methods. Elastography images of 155 patients with adenomyosis and leiomyoma, as well as combined pathology, were analyzed, the elastography diagnosis of which was confirmed by histological examination.\nResults. Leiomyoma and adenomyosis had different elastography characteristics (strain ratios) with different color mapping; their specific characteristics and main differences are determined. Based on sonoelastography, the majority of patients (n=30) were suspected of having uterine fibroids, 14 had adenomyosis, and 42 had adenomyosis and fibroids. Sonoelastography revealed histological signs of adenomyosis in 3 patients with uterine leiomyoma.\nConclusions. Ultrasound examination using compression sonoelastography in such pathological conditions of the myometrium as adenomyosis and leiomyoma, as well as unchanged myometrium, makes it possible to determine changes in the degree of elasticity of the myometrium in the corresponding pathology. Sonoelastography allows the identification of clear distinguishing features of fibroids and adenomyosis. The unchanged myometrium has a certain elasticity, which can be equated to a specific numerical value – the coefficient of deformation. This indicator has different meanings in myoma and adenomyosis, which makes it possible to differentiate these pathological conditions of the myometrium. Compression sonoelastography is able to identify clear distinguishing features of leiomyoma and adenomyosis, and consistency of diagnoses based on sonoelastography and histology is significant but not optimal.\nDownloads\nReferences\nGraziano, A., Lo Monte, G., Piva, I., Caserta, D., Karner, M., Engl, B., Marci, R. 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F. (2014). Real-time elastography for assessment of uterine disorders. Ultrasound in Obstetrics & Gynecology, 43 (2), 218–226. doi: http://doi.org/10.1002/uog.12519\nStoelinga, B., Hehenkamp, W., Nieuwenhuis, L. L., Conijn, M., van Waesberghe, J., Brölmann, H., Huirne, J. (2018). Accuracy and Reproducibility of Sonoelastography for the Assessment of Fibroids and Adenomyosis, with Magnetic Resonance Imaging as Reference Standard. Ultrasound in medicine & biology, 44 (8), 1654–1663.doi: https://doi:10.1016/j.ultrasmedbio.2018.03.027\nDownloads\nPublished\nVersions\n- 2021-07-30 (Version of Record 1.0)\nIssue\nSection\nLicense\nOur journal abides by the Creative Commons CC BY copyright rights and permissions for open access journals.\nAuthors, who are published in this journal, agree to the following conditions:\n1. The authors reserve the right to authorship of the work and pass the first publication right of this work to the journal under the terms of a Creative Commons CC BY, which allows others to freely distribute the published research with the obligatory reference to the authors of the original work and the first publication of the work in this journal.\n2. The authors have the right to conclude separate supplement agreements that relate to non-exclusive work distribution in the form in which it has been published by the journal (for example, to upload the work to the online storage of the journal or publish it as part of a monograph), provided that the reference to the first publication of the work in this journal is included.","source_license":"CC0","license_restricted":false}