{"paper_id":"5b24d43b-3f64-4960-86d7-554c733e4989","body_text":"Abstract\nControversy still exists concerning the optimal treatment of endometriomata in endometriosis and its related infertility. Forty-one women with endometriomata who failed to conceive during previous in vitro fertilization and embryo transfer (IVF-ET) cycles (protocol A) were readmitted for ovum pickup following transvaginal ultrasonic needle-guided aspiration of the endometriomata (protocol B). Following aspiration a significantly higher number of oocytes was recovered (P<0.0006); subsequently, more embryos were transferred, and significantly higher clinical pregnancy rates per cycle (P<0.0001) were achieved. This difference may be directly related to the reduction of extensive ectopic endometrial tissue (endometriomata) with improved ovarian response, follicular accessibility, and most probably, improved oocyte quality.\nSimilar content being viewed by others\nReferences\nChillik C, Acosta AA, Garcia JE, Perera S, Van Uem JF, Rosenwaks Z, Jones HW, Jr: The role of in vitro fertilization in infertile patients with endometriosis. Fertil Steril 1985;44:56–59\nMatson PL, Yovich JL: The treatment of infertility associated with endometriosis by in vitro fertilization. Fertil Steril 1986;46:432–436\nOehninger S, Acosta AA, Kreiner D, Muasher SJ, Jones HW Jr, Rosenwaks Z: In vitro fertilization and embryo transfer (IVF-ET): An established and successful therapy for endometriosis. J Vitro Fertil Embryo Transfer 1988; 5:249–256\nDicker D, Goldman GA, Ashkenazi J, Feldberg D, Voliovitch I, Goldman JA: The value of pre-treatment with gonadotrophin releasing hormone (GnRH) analogue in IVF-ET therapy of severe endometriosis. Hum Reprod 1990;5:418–420\nFeichtinger W, Kemeter P: Transvaginal sector scan sonography for needle guided transvaginal follicle aspiration and other applications in gynecological routine and research. Fertil Steril 1986;45:722–726\nFeichtinger W, Kemeter P: Conservative treatment of ectopic pregnancy by transvaginal aspiration under sonographic control and methotrexate injection. Lancet 1987;1:381–382\nBerkowitz RL, Lynch L, Chitkara V, Wilkin IA, Mehalek KE, Alvarez E: Selective reduction of multiple pregnancies in the first trimester. N Engl J Med 1988;318:1043–1046\nFeldberg D, Ashkenazi J, Dicker D, Yeshaya A, Voliovitch I, Goldman J: Ovarian cyst aspiration during IVF-ET cycles. J Vitro Fertil Embryo Transfer 1988;5:372–375\nFeldberg D, Goldman J, Shelef M, Ashkenazi J, Dicker D, Yeshaya A: Comparison of a fixed and dynamic protocol for embryo transfer in an IVF-ET program. Hum Reprod 1988;3:747–750\nFeldberg D, Goldman JA, Ashkenazi J, Shelef M, Dicker D, Samuel N: Transvaginal oocyte retrieval controlled by vaginal probe for IVF, a comparative study. J Ultrasound Med 1988;7:339–343\nVeeck LL, Wortham JWE Jr, Witmyer J, Sandow BA, Acosta AA, Garcia JE, Jones GS, Jones HW Jr: Maturation and fertilization of morphologically immature human oocytes in a program of in vitro fertilization Fertil Steril 1983;39:594–602\nBeyth Y, Winston RML: Ovum capture and fertility following microsurgical fimbriectomy in the rabbit. Fertil Steril 1981;35:464–466\nMcCornb P, Delbeke L: Decreasing number of ovulations in the rabbit with surgical division of the blood vessels between the fallopian tube and ovary. J Reprod Med 1984;29:827–831\nMolloy D, Martin M, Speirs A, Lopata A, Clarke G, McBain J, Ngv A, Johnston IH: Performance of patients with a “frozen pelvis” in an in vitro fertilization program. Fertil Steril 1987;47:450–455\nEdwards RG, Steptoe PC: Current status of in vitro fertilization. Lancet 1983;2:1265–1269\nMedical Research International and the Society of Assisted Reproductive Technology, The American Fertility Society: In vitro fertilization embryo transfer in the United States: 1987 results from the National IVF-ET Registry. Fertil Steril 1989;51:13–19\nAuthor information\nAuthors and Affiliations\nRights and permissions\nAbout this article\nCite this article\nDicker, D., Goldman, J.A., Feldberg, D. et al. Transvaginal ultrasonic needle-guided aspiration of endometriotic cysts before ovulation induction for in vitro fertilization. J Assist Reprod Genet 8, 286–289 (1991). https://doi.org/10.1007/BF01139786\nReceived:\nAccepted:\nIssue date:\nDOI: https://doi.org/10.1007/BF01139786","source_license":"CC0","license_restricted":false}