{"paper_id":"55d80eb7-a5fd-41aa-bf41-e1658357d281","body_text":"Hubungan Obesitas Menurut Pola Distribusi Lemak Tubuh dengan Kejadian Endometriosis\nDOI:\nhttps://doi.org/10.20961/plexus.v1i4.295Keywords:\nendometriosis; , adipositas; , obesitas, pola distribusi lemakAbstract\nLatar belakang: Endometriosis merupakan salah satu gangguan ginekologis berkaitan hormon estrogen dan berkembang melalui mekanisme peradangan. Pola distribusi jaringan lemak memiliki kaitan dengan hormon estrogen dan peningkatan masa jaringan lemak dapat mempengaruhi sistem pertahanan tubuh. Penelitian ini bermaksud untuk mempelajari hubungan antara keberadaan jaringan lemak berlebih pada regio tertentu dengan endometriosis.\nMetode Penelitian: Studi observasi potong lintang dilakukan pada pasien tindakan pembedahan pada poli obstetri dan ginekologi RSUD Dr. Moewardi dan RS UNS. Sebanyak 87 pasien dibagi menjadi kelompok normal, obesitas sentral, dan obesitas perifer berdasarkan hasil pengukuran indikator antropometri serta dilakukan pendataan konfirmasi endometriosis menurut hasil lab patologi anatomi. Data kemudian dianalisis dengan menggunakan uji kai kuadrat Pearson.\nHasil Peneltian: Subjek pada kelompok endometriosis berusia lebih muda dibandingkan kelompok non endometriosis (p < 0,05). Tidak ada perbedaan berat badan, tinggi badan, dan indeks massa tubuh diantara dua kelompok (p > 0,05). Dismenorrhea dibuktikan berhubungan dengan endometriosis (p > 0,05), namun hubungan tidak ditemukan antara endometriosis dengan infertilitas. Analisis statistik tidak menunjukkan adanya hubungan yang signifikan secara statistik antara obesitas menurut pola distribusi lemak tubuh dengan kejadian endometriosis.\nSimpulan Penelitian: Obesitas menurut pola distribusi lemak tubuh tidak berhubungan dengan kejadian endometriosis.\nKata Kunci: endometriosis; adipositas; obesitas; pola distribusi lemak\nReferences\nAmato, M., Pizzolanti, G., Torregrossa, V., Misiano, G., Milano, S., & Giordano, C. (2014). Visceral Adiposity Index (VAI) Is Predictive of an Altered Adipokine Profile in Patients with Type 2 Diabetes. PLoS ONE, 9(3). doi:doi:10.1371/journal.pone.0091969\nBackonja, U., Buck Louis, G., & Lauver, D. (2016). Overall Adiposity, Adipose Tissue Distribution, and Endometriosis: A Systematic Review. 65(2), 151-66. doi:10.1097/NNR.0000000000000146\nBourgioti, C., Preza, O., Panourgias, P., Chatoupis, K., Antoniou, A., Nikolaidou, M., & Moulopoulos, L. (2017). MR imaging of endometriosis: Spectrum of disease. 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Obesity and endometrial hyperplasia and cancer in premenopausal women: A systematic review. Am J Obstet Gynecol, 214(6), 689.e1-689.e17. doi:10.1016/j.ajog.2016.01.175\nDownloads\nPublished\nIssue\nSection\nLicense\nCopyright (c) 2022 Amira Masiah Syahvira, Eriana Melinawati, Yusuf Ari Mashuri\nThis work is licensed under a Creative Commons Attribution 4.0 International License.\nCopyright @2022. This is an open-access article distributed under the terms of the Creative Commons Attribution 4.0 International License (https://creativecommons.org/licenses/by/4.0/).","source_license":"CC0","license_restricted":false}