{"paper_id":"50e2d959-25cb-46e6-9b34-251d4a344d6e","body_text":"Abstract\nBackground\nFew case reports describing endometriosis in patients with gonadal dysgenesis have been published, but none has reported the presence of adenomyosis in a patient with Turner’s syndrome.\nCase\nA 31-year-old woman with mosaic Turner’s Syndrome (45,X/46,XX/47,XXX) was referred to us because of severe iron deficiency anaemia due to hypermenorrhea and persistent lower abdominal pain for more than six months. She presented normal secondary sex development, normal breast, normal pubic and axillary hair. The external genitalia were also normal. Laboratory examination showed normal gonadotropin, 17beta-estradiol, plasma androgens and cortisol levels. At transabdominal ultrasound a myoma (15×8.5×8 cm) arising from the posterior uterine wall was suspected. The mass was removed during laparotomy. Histologic examination confirmed the presence of the myoma and revealed the presence of focal adenomyosis.\nConclusion\nAdenomyosis and leiomyomata are separate entities but they share a common pathology in that they develop primarily in women of reproductive age and their growth is oestrogen dependent. To our knowledge, this is the first case report in the literature of adenomyosis in a woman who had the Turner’s syndrome.\nSimilar content being viewed by others\nReferences\nBinns BA, Banerjee R (1983) Endometriosis with Turner’s syndrome treated with cyclical oestrogen/progestogen. Case report. Br J Obstet Gynecol 90:581–582\nBösze P, Gaál M, Tóth A, László J (1987) Endometriosis and streak gonad syndrome. Arch Gynecol 240:253–254\nDoty DW, Gruber JS, Wolf GC, Winslow RC (1980) 46, XY pure gonadal dysgenesis: report of 2 unusual cases. Obstet Gynecol 55:61S–65S\nElsheikh M, Dunger DB, Conway GS, Wass JA (2002) Turner’s syndrome in adulthood. Endocr Rev 23:120–140\nFerenczy A (1988) Pathophysiology of adenomyosis. Hum Reprod Update 4:312–322\nMeinen K, Crusius M, Schulz U (1989) Turner syndrome with peritoneal endometriosis and ascites—therapeutic effects of buserelin therapy. Arch Gynecol Obstet 245:943–945\nPeress MR, Sosnowski JR, Mathur RS, Williamson HO (1982) Pelvic endometriosis and Turner’s syndrome. Am J Obstet Gynecol 144:474–476\nRaju GC, Naraynsingh V, Woo J, Jankey N (1988) Adenomyosis uteri: a study of 416 cases. Aust N Z J Obstet Gynaecol 28:72–73\nTazuke SI, Milki AA (2002) Endometrioma of uterine serosa in a woman with mosaic Turner’s syndrome receiving hormone replacement therapy: case report. Hum Reprod 17:2977–2980\nVercellini P, Parazzini F, Oldani S, Panazza S, Bramante T, Crosignani PG (1995) Adenomyosis at hysterectomy: a study on frequency distribution and patient characteristics. Hum Reprod 10:1160–1162\nWang PH, Shyong WY, Lin CH, Chen YJ, Li YF, Chao HT, Yuan CC (2002) Analysis of genetic aberrations in uterine adenomyosis using comparative genomic hybridization. Anal Quant Cytol Histol 24:1–6\nYamamoto T, Noguchi T, Tamura T, Kitawaki J, Okada H (1993) Evidence for estrogen synthesis in adenomyotic tissues. Am J Obstet Gynecol 169:734–738\nAuthor information\nAuthors and Affiliations\nCorresponding author\nRights and permissions\nAbout this article\nCite this article\nFerrero, S., Bentivoglio, G. Adenomyosis in a patient with mosaic Turner’s syndrome. Arch Gynecol Obstet 271, 249–250 (2005). https://doi.org/10.1007/s00404-004-0603-4\nReceived:\nAccepted:\nPublished:\nIssue date:\nDOI: https://doi.org/10.1007/s00404-004-0603-4","source_license":"CC0","license_restricted":false}