{"paper_id":"50dae151-e5af-4cb9-93e5-b6a0371e971e","body_text":"Diagnóstico diferencial: Tumor neuroendócrino de apêndice e endometriose, um relato de caso\nDOI:\nhttps://doi.org/10.70164/jmbr.v3i2.1146Keywords:\nTumor neuroendócrino do apêndice, Endometriose, Apendicectomia, Diag-nóstico diferencial, Imuno-histoquímica, Relato de caso.Abstract\nOs tumores neuroendócrinos do apêndice são neoplasias raras, frequentemente diagnosticadas de forma incidental, enquanto a endometriose profunda é condição comum em mulheres jovens. Relata-se o caso de paciente de 24 anos, com endometriose em acompanhamento, que apresentou achado nodular atípico em exame de imagem. Foi submetida à videolaparoscopia com apendicectomia alargada, cujo exame anatomopatológico revelou tumor neuroendócrino bem diferenciado do apêndice, grau G2 (Ki-67 entre 5% e 8%), estadiamento pT3, com margens livres. Exames complementares não evidenciaram metástases, sendo instituído seguimento clínico multidisciplinar. O caso ressalta a importância do diagnóstico diferencial entre endometriose apendicular e tumor neuroendócrino, bem como o papel fundamental da análise histopatológica para definição terapêutica adequada.\nReferences\nAL‑SHULER, Paulina C.; SCHULTZE, Peter M. Diagnosis of appendiceal neuroendocrine tumors following incidental appendectomy during benign gynecologic laparoscopic surgeries: a case series. Cureus, v. 15, n. 6, e41135, 2023.\nANDRINI, Elisa et al. An update on appendiceal neuroendocrine tumors. Current Treatment Options in Oncology, v. 24, p. 742–756, 2023.\nBECKER, S. et al. Appendiceal involvement in en-dometriosis: systematic review and case series. Fertility and Sterility, v. 107, n. 1, p. 134–142, 2017.\nCHARLTON, J. et al. Appendiceal endometriosis: clinical presentation and surgical management. Journal of Minimally Invasive Gynecology, v. 22, n. 5, p. 845–851, 2015.\nFERRERO, S. et al. Endometriosis and appendiceal tumors: diagnostic challenges. 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World Journal of Surgi-cal Oncology, v. 21, art. 150, 2023.\nDownloads\nPublished\nHow to Cite\nIssue\nSection\nLicense\nCopyright (c) 2026 Lavínia Lopes Bamberg, Felipe Vilanova de França Santana, Antonella Hoffman Maciel, Maria Júlia de Azevedo Barreira de Azevedo; Bruna Correia Sarno; Bruna de Cássia Ribas Benfica dos Santos\nThis work is licensed under a Creative Commons Attribution 4.0 International License.","source_license":"CC0","license_restricted":false}