{"paper_id":"4d82b73d-bbcf-419c-a25e-074c7d9574cc","body_text":"The fear and anxiety that patients experience in the dental office, especially with dental injections, which are also referred to as\n\"needle-phobia\" or \"blenophobia\", is the most unpleasant element of being a patient [ 1 ].\nInhalation sedation has also been used in place of injectable local anesthetics during dental operations. Nitrous oxide/oxygen is the\nmost commonly used inhalation anesthetic in dentistry. Although nitrous oxide/oxygen has some analgesic properties, its potency (high\nminimal alveolar concentration) makes it unsuitable for usage in substitution of local anesthetics since it may not always have the\ndesired effects on all individuals. The equipment and logistics of safe delivery, such as operatory space, equipment charges, supply\ncosts and patient costs, are further disadvantages of nitrous oxide. Thus, the goal was to provide a secure and efficient substitute for\ninhalation sedation and injectable local anesthetics that could be utilized in dental offices [ 2 ].\nElectronic dental anesthesia (EDA) or transcutaneous electrical nerve stimulation has been utilized to help manage pain in adults and\nchildren in recent years. Transcutaneous electrical nerve stimulation is a technology based on the well-established pain control\nhypothesis put forth by Malzack and Wall in 1965 that offers a promising low current dental anesthetic delivery approach. It is widely\nutilized to relieve pain from a variety of illnesses, including endometriosis, arthritis, sports injuries, multiple sclerosis,\nfibromyalgia, severe diabetic neuropathy and spinal cord injury, in many medical and paramedical professions [ 3 ].\nThere is still a lack of research on the use of transcutaneous electrical nerve stimulation as an anesthetic device, even though Shane and\nKessler initially reported its usage in dentistry in 1967. Patients can accept it broadly and it's safe and non-invasive. Transcutaneous\nelectrical nerve stimulation has been shown to be an effective way to manage discomfort during some dental operations and to offer a\nconsiderable improvement over other common local anesthetic therapies [ 4 ]. According to Pashley\n et al.  pain during needle injection is caused by administering the anesthetic fluid too quickly or forcefully.\nFurthermore, the flow rate and pressure rate cannot be properly controlled with manual conventional syringes, leading to uneven and\nuncomfortable injections. Reducing the pain and suffering related to the administration of local anesthesia might improve the patient's\ncomfort and happiness. In actuality, the primary objective of any physician is to provide local anesthetic without causing pain\n[ 5 ]. Therefore, it is of interest to clinically evaluate the efficiency of transcutaneous\nelectrical nerve stimulation in extraction technique as a prospective substitute for injectable local anesthetics in geriatric patients,\nin order to provide a realistic alternative in the dentist's pain control arsenal.\n\nThis comparative prospective study was carried out in the department of oral and maxillofacial surgery at Vivekananda Dental College\nfor Women in the year 2022. The study was approved by the institutional ethical committee prior to the study (No: VDCW/IEC/308/2022).\nEvery single patient was informed about the surgical technique and gave their informed consent. Study comprised of 20 patients in total,\nwhere it was divided into two groups with 10 patients in each group. The patients' lots, which served as a straightforward random\nsampling technique, divided the two extraction groups. Ten patients from Group A and ten patients from Group B, respectively, received\nextractions using 2% lignocaine and transcutaneous electrical nerve stimulation, respectively. It took us two months to complete our\nstudy session. For every patient, a proforma comprising name, age, sex, address, chief complaint, medical history, prior dental history,\nintraoral examinations and past medical history was employed. Adult patients aged 45-50 year old who are healthy and cooperative with\ngrade III mobility on clinical examination were included in our study. We excluded the patients who are under corticosteroids, having\nsystemic illness like heart disease, cardiac pacemakers, seizure disorders and neurologic disorders. The flowchart of the study is\nexplained in (Figure 1 - see PDF).\nThe materials used here were two channel Transcutaneous Electrical Nerve Stimulator T.E.N.S. marketed by Sheetla-Tec Industries (An\nISO 9001: 2015 Certified Company) (Figure 2 - see PDF), Haryana, Electrode gel (Figure 3 - see PDF), 25 Gauge needle and Lignocaine 2%.\nFigure 4 (see PDF) shows the electrode pads and control unit that come with the T.E.N.S. Two separate galvanic channels make up its\ncomposition. A fixed pulse rate and amplitude control of up to 220 mA can be achieved by each channel, which is powered by a 9 V battery\nwith frequencies ranging from 2 Hz to 150 Hz. Each channel also has a frequency control knob.\n\nThe primary outcome of our research was to assess and contrast the pain following extraction using transcutaneous electrical nerve\nstimulation and 2% lignocaine. A visual analog scale was used to measure the degree of pain. Patients were asked to rate their level of\npain on a scale of 0 to 10. Here, representation of a cheerful patient at one end and a sobbing patient at the other represent 0 and 10,\nrespectively, representing \"absolutely no pain\" and \"the worst pain imaginable\", Using a prick test, the secondary outcome evaluates the\nanesthetic impact of transcutaneous electrical nerve stimulation and 2% lignocaine. Pricking the patient's marginal gingiva, connected\ngingiva and the area around the tooth allowed researchers to determine the anesthetic impact. Patients were then asked to raise their\nhands if they felt any discomfort.\n\nBefore starting the actual treatment, the patient was given a brief explanation of the method and the electrode pad placement was\ndetermined. The electrode pad implantation location was gently cleansed with surgical spirit to remove any oils or anything that would\nimpede the flow of current. Electrode gel was added to the electrode pads prior to placement. Once the electrode pads were in position,\nthe patient was told to maintain their lips open during the procedure. Surgical tape was used to hold the electrode pads firmly in place\nand prevent them from moving. After turning on the device, the researcher increased the amplitude knob to progressively increase the\npatient's level of electronic anesthesia until a discernible sensation began to occur. In order to give the patient time to get used to\nthe new sensation of electronic anesthesia, this amplitude level was kept at this level for 20 seconds. After then, the cycle was\nrepeated with increasing amplitude until quivering or fasciculation was noticed in close proximity to the pads. The lower eyelid and\nupper lip twitched in cases involving the maxillary arch, whereas the lower lip twitched in cases involving the mandibular arch. This\nwas the lowest feasible level, called the \"therapeutic level of stimulation\" and the treatment could continue at it. If there was pain\nor discomfort felt by the patient during the process, the amplitude was gradually increased to \"dail-out discomfort\" within an acceptable\nrange. When experiencing any discomfort, the patient was instructed to raise their hand and the transcutaneous electrical nerve\nstimulation amplitude was decreased while the researcher adjusted the stimulation intensity. Following the procedure, all controls were\nreturned to their initial state of zero. After turning off the equipment, the connections were eventually cut.\n\nThe statistical package for social science (SPSS), version 25 was used for all of the statistical analysis. The samples were examined\nto see if they were regularly distributed using the Kolmogorov-Smirnov test. Furthermore, the outcome of the histogram was uneven around\nthe mean of the distribution, leading us to conclude that the data were not normally distributed. The data were shifted to the left, as\nindicated by their negative kurtosis. Thus, the following resulted from doing the Mann-Whitney U test ( Table 1 ).\n10 patients had undergone extraction under transcutaneous electrical nerve stimulation, out of which 4 were male patients and 6 were\nfemale patients and 10 patients had undergone extraction under 2% Lignocaine out of which 4 were male patients and 6 were female\npatients ( Table 2  &  Table 3 ). The amount of pain\nexperienced throughout the surgery was measured using the visual analog scale. Patients' proposed Visual Analog Scale scores fell into\nfour categories: 0 represented no pain; 1-3 represented mild pain; 4-6 represented moderate to severe pain; 7-9 represented very severe\npain and 10 represented the worst possible pain.\n\nPain is the most unpleasant and uncomfortable part of dentistry and it can lead to a patient acting significantly less cooperatively\nin the dental office. It is distressing that the devices meant to ease patients' pain also exacerbate their discomfort and worry. While\ntranscutaneous electrical nerve stimulation offers the advantages of being non-invasive and safe to use, it is still far more effective\nthan local anesthesia for minor dental procedures in relieving pain associated with injections. The purpose of this study was to better\nunderstand the anesthetic effect of transcutaneous electrical nerve stimulation during extractions and to determine whether this\ntechnique may replace local anesthesia in permanent teeth extractions of grade III mobility. For this reason, Grade III extractions\nperformed in the Oral and Maxillofacial Surgery department were chosen for this investigation. \"Transcutaneous Electrical Nerve\nstimulation is the direct stimulation of the nerves by short-duration, small amplitude electric pulses,\" according to All good\n[ 6 ]. Three types of transcutaneous electrical nerve stimulation units are identified. For both\nacute postoperative pain and chronic temporomandibular joints pain, the most common mode utilized is high-frequency (25-150 Hz)\nelectronic dental anesthesia. When high-frequency transcutaneous electrical nerve stimulation becomes unusable due to accommodation when\ntreating chronic pain, low frequency (2-10 Hz) is employed. The measurement of precise vertical dimension of rest and the treatment of\npersistent temporomandibular joints pain are two further applications for ultralow-frequency (0.5-2 Hz). In order to prevent adverse\nskin reactions, dental procedures should only employ a balanced, biphasic wave shape with a zero net DC component [ 7 ].\nThe application of transcutaneous electrical nerve stimulation was founded on a number of interconnected theories about the transmission\nof pain and how to block these pathways. The first of these theories is the gate control theory proposed by Melzack and Wall\n[ 3 ]. Another explanation for the workings of transcutaneous electrical nerve stimulation is that\nendorphins are released as a result of electric stimulation. These endorphins attach to opiate receptors and prevent the transmission of\npainful impulses. According to a different idea, stimulation-induced analgesia involves the creation of dopamine, norepinephrine and\nserotonin and the analgesic impact of transcutaneous electrical nerve stimulation is directly correlated with a rise in serotonin. It is\ncurrently unclear how exactly electronic anesthesia reduces pain, though it may work by combining one or more theories. In the first\ngroup, transcutaneous electrical nerve stimulation was used to extract teeth from ten patients. These were mobile teeth of grade III,\ntheir roots either intact or resorbed. The mean Visual Analog Scale score for this group was 0.40, meaning that some patients had\nmoderate pain or discomfort during extraction and that the clinician thought the anesthetic was effective. The scale showed p<0.143\nto be extremely significant. In contrast, 10 patients in the second group underwent extractions with 2% lignocaine. They were also grade\nIII mobile teeth, their roots either resorbed or undamaged. The Visual Analog Scale data for this group revealed a mean score of 0.00,\nmeaning that not a single patient reported feeling pain or discomfort during the extraction process.  Table 4 \ndisplays a p-value of 0.000 as indicated by the scale. The conventional Prick test was used to validate both groups. Nonetheless, 75% of\nthe patients showed a positive response to transcutaneous electrical nerve stimulation in comparison with lignocaine. In terms of\nhemostasis and wound healing, transcutaneous electrical nerve stimulation proved to be more effective for 100% of the patients.\nAccording to some hypotheses, transcutaneous electrical nerve stimulation improves patients' comfort after surgery. It looks that there\nare two ways that this is achieved. Initially, teeth do not have to heal from a blood flow loss caused by injection-based local\nanesthetic since the blood flow to the treated area is boosted. Second, the enhanced feeling of wellbeing may persist for several hours\nfollowing the removal of the electrodes due to the production of endogenous opioids, such as endorphins and enkephalins. None of our\npatients experienced skin redness or responses to the electrodes, despite some studies showing transient skin redness over the electrode\nimplantation site as a result of increased blood circulation to that area [ 8 ,\n 9 ,  10 - 11 ].\n\nTranscutaneous electrical nerve stimulation is far more effective than local anesthesia for relieving dental injection-related pain\nas it is safe and non-invasive. Therefore, electronic dental anesthesia transcutaneous electrical nerve stimulation is a useful addition\nto a dentist's toolkit. The therapeutic effectiveness of these anesthetic modalities will be maximized by accurately utilizing modern\ntechnology such as artificial intelligence in electronic dental anesthesia for pain threshold assessment which will soon surpass the\nneed of needles. It should be noted that validation using a large sample size is highly relevant.","source_license":"CC-BY-4.0","license_restricted":false}